Results 11 to 20 of about 24,765 (260)
The Application of Microfluidic Technologies in Aptamer Selection
Frontiers in Cell and Developmental Biology, 2021 Aptamers are sequences of single-strand oligonucleotides (DNA or RNA) with potential binding capability to specific target molecules, which are increasingly used as agents for analysis, diagnosis, and medical treatment.
Yang Liu +14 more
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Biochemical mechanism of erastin-induced ferroptotic cell death in neuronal cells
Acta Biochimica et Biophysica Sinica, 2023 Ferroptosis is a new form of nonapoptotic cell death closely associated with glutathione (GSH) peroxidase 4 inhibition and/or GSH depletion, resulting in the accumulation of cellular iron and lipid peroxides.
Hou Ming-Jie, Wang Pan, Zhu Bao Ting
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Frontiers in Veterinary Science, 2020 This study was conducted to investigate the therapeutic effect of allogeneic adipose-derived MSCs on dogs with hip osteoarthritis (OA). Twenty dogs with bilateral osteoarthritis of the coxofemoral (hip) joint, diagnosed by a veterinarian through physical
Chad B. Maki +7 more
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Cancer Treatment and Research Communications, 2021 : Resveratrol (RES), a dietary phenolic compound, was reported to have cancer chemoprotective and chemotherapeutic effects. Earlier we unexpectedly observed that RES has a growth-enhancing effect in some breast cancer cells and can diminish the ...
Masayuki Fukui +3 more
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Patient-Specific
mBio, 2016 A 2-year longitudinal microbiome study of 22 patients who underwent colectomy with an ileal pouch anal anastomosis detected significant increases in distinct populations of Bacteroides during 9 of 11 patient visits that coincided with inflammation ...
Joseph H. Vineis +10 more
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Carbohydrate-Modified Electrode Surfaces Sensitive to ß-Glucosidase Enzyme Activity
International Journal of Electrochemical Science, 2014 A surface modification which renders a carbon electrode sensitive to β-glucosidase enzyme activity is reported. 2-Nitro-4-(4-diazophenoxymethyl)-phenyl β-D-glucopyranoside was prepared in four steps from the known starting material 2-nitro-4-benzyloxy 2 ...
Emily M. Ervin +5 more
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Molecular Imaging of Hydrolytic Enzymes Using PET and SPECT
Molecular Imaging, 2017 Hydrolytic enzymes are a large class of biological catalysts that play a vital role in a plethora of critical biochemical processes required to maintain human health.
Brian P. Rempel BSc, PhD +2 more
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Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A [PDF]
Journal of Medicinal Chemistry, 2021 Published by ACS, Washington ...
Wortmann, Lars +20 more
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Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069
Journal of Medicinal Chemistry, 2022 The ligand-activated nuclear receptor peroxisome-proliferator-activated receptor-γ (PPARG or PPARγ) represents a potential target for a new generation of cancer therapeutics, especially in muscle-invasive luminal bladder cancer where PPARγ is a critical lineage driver.
Douglas L. Orsi +19 more
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Uncultivated Viral Populations Dominate Estuarine Viromes on the Spatiotemporal Scale
mSystems, 2021 Viruses are ubiquitous and abundant in the oceans, and viral metagenomes (viromes) have been investigated extensively via several large-scale ocean sequencing projects. However, there have not been any systematic viromic studies in estuaries.
Mengqi Sun +5 more
doaj +3 more sources