Results 121 to 130 of about 827,464 (311)
Circumferential Periosteal Release to Treat Paediatric Leg Length Discrepancy: Medium Term Outcomes
This study aims to report the medium term outcomes of circumferential periosteal release of the distal femur and distal tibia in treating paediatric leg length discrepancy (LLD).
Jan Herman Kuiper +5 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Effects of discrepancy between imagined and perceived sounds on the N2 component of the event-related potential [PDF]
Two experiments were conducted to examine whether the N2 component of the event-related potential (ERP), typically elicited in a S1-S2 matching task and considered to reflect mismatch process, can still be elicited when the S1 was imagined instead of ...
Mai, Xiaoqin +5 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
On the Linear and Hereditary Discrepancies
Let \(A\) be an \(m\times n\) 0-1-matrix (incidence matrix of a set system) and let \[ \begin{aligned} \text{disc } (A)&=\min_{x\in \{-1, 1\}^n} \|Ax \|_\infty\\ \text{herdisc } (A)&=\max_{B \text{ submatrix of } A} \text{disc }(B)\\ \text{lindisc}_1 (A)&=\max_{w\in\{-1, 0, 1\}^n} \min_{x\in\{-1, 1\}^n} \|A(x-w)\|_\infty \end{aligned} \] The author ...
openaire +1 more source
A discrepancy principle for Poisson data: uniqueness of the solution for 2D and 3D data
This paper is concerned with the uniqueness of the solution of a nonlinear equation, named discrepancy equation. For the restoration problem of data corrupted by Poisson noise, we have to minimize an objective function that combines a data-fidelity ...
Ruggiero, Valeria, Bonettini, Silvia
core
The stable solution of ill-posed non-linear operator equations in Banach space requires regularization. One important approach is based on Tikhonov regularization, in which case a one-parameter family of regularized solutions is obtained.
Anzengruber, Stephan W. +2 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

