Results 141 to 150 of about 827,464 (311)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Generation of non-uniform low-discrepancy sequences in the multidimensional case
Journal of Numerical Analysis and Approximation Theory, 2006 In this paper we extend the results we obtained in an earlier paper, from the one-dimensional case to the \(s\)-dimensional case. We propose two inversion type methods for generating \(G\)-distributed low-discrepancy sequences in \([0,1]^{s}\), where \(G\
Natalia Roşca
doaj +2 more sources
, 2013 Studies have suggested associations between personality dimensions and body image constructs, but these have not been conclusively established. In two studies, we examined direct associations between the Big Five dimensions and two body image constructs,
Swami, V. +8 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The concept of a product defect, its causes and theoretical aspects of management
Taikomieji Moksliniai Tyrimai, 2022 The concept of product defect and its synonyms used in the scientific literature are analyzed in the article. The types and causes of product defects are systematised on the basis of relevant regulatory documents, such as the Blue Guide to the ...
Milda Zenovjeva, Rasa Balvočiūtė
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
'Shocking' discrepancies [PDF]
Europace, 2010 Stavros I, Chrysostomakis +1 more
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Aspects of "Discrepancy" in Clinical Psychology : investigating "Body Image"
, 2009 P(論文)原著Articledepartmental bulletin ...
Otsuka, Hisashi +5 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source