Results 81 to 90 of about 23,280,557 (293)

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Failure diagnosis in real time stochastic discrete event systems

open access: yesEngineering Science and Technology, an International Journal, 2015
Discrete Event System (DES) has been used for Failure Detection and Diagnosis (FDD) of a wide range of systems. For real time systems, timed DES based frameworks diagnose failures leading to violation of delays or deadlines.
Chaitali Biswas Dutta, Utpal Biswas
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

W-Stability of Multistable Nonlinear Discrete-Time Systems

open access: yesDiscrete Dynamics in Nature and Society, 2012
Motivated by the importance and application of discrete dynamical systems, this paper presents a new Lyapunov characterization which is an extension of conventional Lyapunov characterization for multistable discrete-time nonlinear systems. Based on a new
Zhishuai Ding, Guifang Cheng, Xiaowu Mu
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

Controllability Analysis of Linear Discrete Time Systems with Time Delay in State

open access: yesAbstract and Applied Analysis, 2012
The controllability issues for linear discrete-time systems with delay in state are addressed. By introducing a new concept, the minimum controllability realization index (MinCRI), the characteristic of controllability is revealed.
Hong Shi, Guangming Xie, Wenguang Luo
doaj   +1 more source

On the Maximal Output Admissible Set for a Class of Bilinear Discrete-time Systems. [PDF]

open access: yesInt J Control Autom Syst, 2021
Benfatah Y   +3 more
europepmc   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Self-synchronization of Thomson self-oscillatory systems in discrete time

open access: yesФизика волновых процессов и радиотехнические системы, 2015
The effect arising in discrete time at interaction of self-oscillations with higher harmonics of the main frequency is described. It is shown that it is similar to effect of capture of the frequency (synchronization) of self-oscillations by an external ...
V.V. Zaitsev, O.V. Zaitsev, I.V. Stulov
doaj  

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