Results 51 to 60 of about 3,314,720 (268)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

An Effective Corner Increment-Based Algorithm for the Two-Dimensional Strip Packing Problem

open access: yesIEEE Access, 2018
The 2-D strip packing problem is an NP-hard combinatorial optimization problem. Given a strip with fixed width and infinite height, the aim of strip packing is to pack a set of rectangles with known widths and heights into the strip such that the used ...
Zhen Chen, Jianli Chen
doaj   +1 more source

Discrete Hamilton-Jacobi Theory

open access: yes, 2011
We develop a discrete analogue of Hamilton-Jacobi theory in the framework of discrete Hamiltonian mechanics. The resulting discrete Hamilton-Jacobi equation is discrete only in time.
Anthony M. Bloch   +3 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Independent resolving sets in graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2021
Let be a connected graph. Let be a subset of V with an order imposed on W. The k-vector is called the resolving vector of v with respect to W. The set W is called a resolving set if for any two distinct vertices In this paper we investigate the existence
B. Suganya, S. Arumugam
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Systematic evaluation of the isolated effect of tissue environment on the transcriptome using a single-cell RNA-seq atlas dataset

open access: yesBMC Genomics
Background Understanding cellular diversity throughout the body is essential for elucidating the complex functions of biological systems. Recently, large-scale single-cell omics datasets, known as omics atlases, have become available.
Daigo Okada   +4 more
doaj   +1 more source

ANALYSIS OF A TRANSPORT PROCESS USING HYBRID PETRI NETS [PDF]

open access: yesFiabilitate şi Durabilitate, 2013
Purpose of the paper is to analyze the Petri net model, to describe the transport process, part of amanufacturing system and its dynamics.A hibrid Petri net model is built to describe the dinamics of the transport process manufacturingsystem ...
Elisabeta Mihaela CIORTEA   +2 more
doaj  

A comparison of dimensional and discrete models for the representation of perceived and induced affect in response to short musical sounds

open access: yesFrontiers in Psychology, 2023
IntroductionIn musical affect research, there is considerable discussion on the best method to represent affective response. This discussion mainly revolves around the dimensional (valence, tension arousal, energy arousal) and discrete (anger, fear ...
Iza Ray Korsmit   +3 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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