Results 41 to 50 of about 880,492 (299)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

To the solution of the equation of the radiation transfer transformation by the method of discrete ordinates

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2017
In work the method of discrete ordinates is applied to the solution of a problem of transfer of radiation in three-dimensional statement. Results with use of S4-, S6-, S8-approximations are received and comparison with data of other authors is carried ...
A. V. Sadykov, M. A. Butyakov
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Periodically Kicked Rotator with Power-Law Memory: Exact Solution and Discrete Maps

open access: yesFractal and Fractional
This article discusses the transformation of a continuous-time model of the fractional system into a discrete-time model of the fractional system. For the continuous-time model, the exact solution of the nonlinear equation with fractional derivatives ...
Vasily E. Tarasov
doaj   +1 more source

Quasi-harmonic self-oscillations in discrete time: analysis and synthesis of dynamic systems

open access: yesФизика волновых процессов и радиотехнические системы, 2022
For sampling of time in a differential equation of movement of Thomson type oscillator (generator) it is offered to use a combination of the numerical method of finite differences and an asymptotic method of the slowl-changing amplitudes.
Valery V. Zaitsev, Alexander V. Karlov
doaj   +1 more source

Bounds for Approximate Discrete Tomography Solutions [PDF]

open access: yesSIAM Journal on Discrete Mathematics, 2013
In earlier papers we have developed an algebraic theory of discrete tomography. In those papers the structure of the functions $f: A \to \{0,1\}$ and $f: A \to \mathbb{Z}$ having given line sums in certain directions have been analyzed. Here $A$ was a block in $\mathbb{Z}^n$ with sides parallel to the axes.
Lajos Hajdu, Robert Tijdeman
openaire   +3 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Stability of Approximation in Discrete Optimization [PDF]

open access: yes, 2006
One can try to parametrize the set of the instances of an optimization problem and look for in polynomial time achievable approximation ratio with respect to this parametrization. When the approximation ratio grows with the parameter, but is independent of the size of the instances,then we speak about stable approximation algorithms.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Rapid Prototyping of Field Programmable Gate Array-Based Discrete Cosine Transform Approximations

open access: yesEURASIP Journal on Advances in Signal Processing, 2003
A method for the rapid design of field programmable gate array (FPGA)-based discrete cosine transform (DCT) approximations is presented that can be used to control the coding gain, mean square error (MSE), quantization noise, hardware cost, and power ...
Trevor W. Fox, Laurence E. Turner
doaj   +1 more source

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