Results 91 to 100 of about 2,437,029 (311)

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

We Know What You Choose! External Validity of Discrete Choice Models [PDF]

open access: yes
For over the last thirty years the multinomial logit model has been the standard in choice modeling. Development in econometrics and computational algorithms has led to the increasing tendency to opt for more flexible models able to depict more ...
R. Karina Gallardo, Jaebong Chang
core  

A Discrete Choice Model for Ordered Alternatives

open access: yesEconometrica, 1987
A generalization of the multinomial logit (MNL) model is developed in which discrete alternatives are ordered so as to induce stochastic correlation among alternatives in close proximity. It is designed for situations where the alternatives are ordered, but is more flexible than previous ordered models.
openaire   +3 more sources

Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit   +10 more
wiley   +1 more source

Combining discrete and continuous mixing approaches to accommodate heterogeneity in price sensitivities in environmental choice analysis [PDF]

open access: yes
Data from a discrete choice experiment aimed at eliciting the demand for recreational walking trails on farmland in the Republic of Ireland is used to explore the consequences of misspecifying the cost coefficient.
Campbell, Danny   +3 more
core  

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

open access: yesArthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang   +21 more
wiley   +1 more source

Truth and consequence: a look behind the Vatican's ban on contraception

open access: yes, 2008
With these words slamming the door on Catholics’use of modern contraceptives, Pope Paul VI cleaved the Catholic church into irreconcilable factions 40 years ago. The majority, unable to reconcile the rigid encyclical with their need for an updated sexual
Catholics for Choice
core  

Preferences of older patients regarding hip fracture rehabilitation service configuration: A feasibility discrete choice experiment

open access: yesJournal of Rehabilitation Medicine, 2018
Objective: As part of a wider feasibility study, the feasibility of gaining older patients’ views for hip fracture rehabilitation services was tested using a discrete choice experiment in a UK context.
Joanna M. Charles   +5 more
doaj   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah   +4 more
wiley   +1 more source

Lexicographic Preferences in Discrete Choice Experiments: Consequences on Individual-Specific Willingness to Pay Estimates [PDF]

open access: yes
In discrete choice experiments respondents are generally assumed to consider all of the attributes across each of the alternatives, and to choose their most preferred.
W. George Hutchinson   +2 more
core  

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