Results 41 to 50 of about 153,229 (263)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Patients’ Preferences and Willingness to Pay for Solid Forms of Oral Medications—Results of the Discrete Choice Experiment in Polish Outpatients

open access: yesPharmaceutics, 2020
Purpose: Personal preferences play an important role in the patients’ decision process whether to adhere to treatment, or not. The purpose of this study is to assess Polish outpatients’ preferences for solid forms of oral medications across ...
Marta Kurczewska-Michalak   +2 more
doaj   +1 more source

Robust inattentive discrete choice

open access: yesProceedings of the National Academy of Sciences
Rational inattention models characterize optimal decision-making in data-rich environments. In such environments, it can be costly to look carefully at all of the information. Some information is much more salient for the decision at hand and merits closer scrutiny.
Hansen, Lars Peter   +2 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Discrete Choice Modelling for Transportation [PDF]

open access: yes, 2001
This paper discusses important developments in discrete choice modeling for transportation applications. Since there have been a number of excellent recent surveys of the discrete choice literature aimed at transportation applications ( see Bhat, 1997 and 2000a), this paper will concentrate on new developments and areas given less weight in recent ...
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Consumer Behavior in the Choice of Mode of Transport: A Case Study in the Toledo-Madrid Corridor

open access: yesFrontiers in Psychology, 2017
Within the context of the consumption of goods or services the decisions made by individuals involve the choice between a set of discrete alternatives, such as the choice of mode of transport.
Ana I. Muro-Rodríguez   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Combining Actual and Contingent Behavior Data to Model Farmer Adoption of Water Quality Protection Practices

open access: yesJournal of Agricultural and Resource Economics, 1997
Using farmer responses to contingent valuation method (CVM) survey data in combination with actual market data from four watershed regions in the United States, this study estimates the minimum incentives payments a farmer would accept in order to adopt ...
Joseph C. Cooper
doaj   +1 more source

Optimasi Tarif Kereta Bandara Soekarno-Hatta dengan Model Permintaan Berbasis Discrete Choice Experiment

open access: yesJurnal Teknik Sipil, 2021
Penelitian ini bertujuan menentukan tarif optimal Kereta Bandara Soekarno Hatta dengan fungsi permintaan yang diturunkan dengan pendekatan discrete-choice experiment.
Fransiscus Rian Pratikto   +1 more
doaj   +1 more source

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