Results 41 to 50 of about 152,792 (262)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The limits of identification in discrete choice
Games and Economic BehaviorThis paper uncovers tight bounds on the number of preferences permissible in identified random utility models. We show that as the number of alternatives in a discrete choice model becomes large, the fraction of preferences admissible in an identified model rapidly tends to zero. We propose a novel sufficient condition ensuring identification, which is
Chambers, Christopher P. +1 more
openaire +4 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
FishesAquaculture in developing countries, including Mexico, primarily consists of artisanal activities characterized by low-scale production. No studies in these regions has analyzed consumer preferences regarding aquaculture products, specifically for snook ...
Marco Antonio Almendarez-Hernández +5 more
doaj +1 more source
Pharmaceutics, 2020 Purpose: Personal preferences play an important role in the patients’ decision process whether to adhere to treatment, or not. The purpose of this study is to assess Polish outpatients’ preferences for solid forms of oral medications across ...
Marta Kurczewska-Michalak +2 more
doaj +1 more source
Discrete Choice Modelling for Transportation [PDF]
, 2001 This paper discusses important developments in discrete choice modeling for transportation applications. Since there have been a number of excellent recent surveys of the discrete choice literature aimed at transportation applications ( see Bhat, 1997 and 2000a), this paper will concentrate on new developments and areas given less weight in recent ...
openaire +3 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Consumer Behavior in the Choice of Mode of Transport: A Case Study in the Toledo-Madrid Corridor
Frontiers in Psychology, 2017 Within the context of the consumption of goods or services the decisions made by individuals involve the choice between a set of discrete alternatives, such as the choice of mode of transport.
Ana I. Muro-Rodríguez +2 more
doaj +1 more source
On substitutability and complementarity in discrete choice models
Operations Research Letters, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Guiyun Feng +2 more
openaire +4 more sources