Results 41 to 50 of about 130,186 (259)

50 years of behavioral models for transportation and logistics

open access: yesEURO Journal on Transportation and Logistics
Fifty years ago, transportation and logistics problems were primarily analyzed either from a supply-side or a demand-side perspective, with the fields of operations research and demand modeling evolving separately.
Léa Ricard, Michel Bierlaire
doaj   +1 more source

A EVALUATION OF CONSUMER’S PREFERENCES IN THE CLUJ-NAPOCA RETAIL MARKET BASED ON A MULTINOMIAL LOGIT MODEL [PDF]

open access: yesManagement & Marketing, 2009
A long period of time investors were interested in the Bucharest market, but the need for investment in the rest of the country, coupled with the high potential markets present there, resulted in increasingly more investors interested in Romania ...
Ciprian Marcel POP   +2 more
doaj  

Semi-Supervised Learning for Discrete Choice Models [PDF]

open access: yesIEEE Transactions on Intelligent Transportation Systems, 2019
We introduce a semi-supervised discrete choice model to calibrate discrete choice models when relatively few requests have both choice sets and stated preferences but the majority only have the choice sets. Two classic semi-supervised learning algorithms, the expectation maximization algorithm and the cluster-and-label algorithm, have been adapted to ...
Jie Yang 0045   +2 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Discrete Choice Modeling [PDF]

open access: yes, 2009
We detail the basic theory for models of discrete choice. This encompasses methods of estimation and analysis of models with discrete dependent variables. Entry level theory is presented for the practitioner. We then describe a few of the recent, frontier developments in theory and practice.
openaire   +2 more sources

Dynamic Discrete Choice Structural Models: A Survey [PDF]

open access: yesSSRN Electronic Journal, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Victor Aguirregabiria, Pedro mira
openaire   +3 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Comparing discrete choice and machine learning models in predicting destination choice

open access: yesEuropean Transport Research Review
Destination choice modeling has long been dominated by theory-based discrete choice models. Simultaneously, machine learning has demonstrated improved predictive performance to other fields of discrete choice modeling.
Ilona Rahnasto, Martijn Hollestelle
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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