Results 51 to 60 of about 130,186 (259)

Implications of Thresholds in Discrete Choice Modelling

Transport Reviews, 2006
Abstract Individual choices are affected by complex factors and the challenge consists of how to incorporate these factors in order to improve the realism of the modelling work. The presence of limits, cut‐offs or thresholds in the perception and appraisal of both attributes and alternatives is part of the complexity inherent to choice‐making behaviour.
Cantillo, Victor, Ortuzar, Juan De Dios
openaire   +4 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Fully Data-Driven but Interpretable Human Behavioural Modelling With Differentiable Discrete Choice Model

IEEE Access
Discrete choice models are essential for modelling various decision-making processes in human behaviour. However, the specification of these models has depended heavily on domain knowledge from experts, and the fully automated but interpretable modelling
Fumiyasu Makinoshima, Tatsuya Mitomi, Fumiya Makihara, Eigo Segawa   +3 more
doaj   +1 more source

Diagnostics in some discrete choice models

Computational Statistics & Data Analysis, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nagel, Herbert, Hatzinger, Reinhold
openaire   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Ekstraksi Ciri Produktivitas Dinamis untuk Prediksi Topik Pakar dengan Model Discrete Choice

Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2018
Rekomendasi pakar yang aktif atau produktif dapat mendukung kelancaran kolaborasi penelitian. Kegiatan publikasi dan sitasi menjadi indikasi produktivitas seorang pakar.
Diana Purwitasari, Chastine Fatichah, Surya Sumpeno, Mauridhi Hery Purnomo   +3 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Research on the preference of community health communication service utilization by patients with cardiovascular diseases in China

BMC Public Health
Objectives This study sought to examine cardiovascular patients’ preferences for community health communication and to offer recommendations to boost the engagement with health communication programs.
Wei Liu, Junhong Dong, Ying Zhang, Haojie Li, Jiayue Sun, Tianyu Xu, Zehui Li, Guangsheng Wan, Hui Yin   +8 more
doaj   +1 more source