Results 51 to 60 of about 8,708,943 (308)

Consumer Behavior in the Choice of Mode of Transport: A Case Study in the Toledo-Madrid Corridor

Frontiers in Psychology, 2017
Within the context of the consumption of goods or services the decisions made by individuals involve the choice between a set of discrete alternatives, such as the choice of mode of transport.
Ana I. Muro-Rodríguez, Israel R. Perez-Jiménez, Santiago Gutiérrez-Broncano   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Dynamic Discrete Choice Models: Methods, Matlab Code, and Exercises

, 2020
Matlab package for teaching and learning the econometrics of dynamic discrete choice models. See http://ddc.abbring.org for extensive documentation and exercises. See https://github.com/jabbring/dynamic-discrete-choice for a public Github repository.
Jaap H. Abbring, Tobias J. Klein
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Advancing freight demand prediction: Unified destination and mode choice models in extra-urban transportation

Asian Journal of Shipping and Logistics
Freight transportation modeling represents the economic demand for moving goods across spatial networks. Traditional models often treat transportation mode and destination choice as separate processes.
Shahriar Afandizadeh, Amin Akhoundi, Hamid Mirzahossein   +2 more
doaj   +1 more source

Implications of Thresholds in Discrete Choice Modelling

Transport Reviews, 2006
Abstract Individual choices are affected by complex factors and the challenge consists of how to incorporate these factors in order to improve the realism of the modelling work. The presence of limits, cut‐offs or thresholds in the perception and appraisal of both attributes and alternatives is part of the complexity inherent to choice‐making behaviour.
Cantillo, Victor, Ortuzar, Juan De Dios
openaire   +4 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Diagnostics in some discrete choice models

Computational Statistics & Data Analysis, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nagel, Herbert, Hatzinger, Reinhold
openaire   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source