Results 31 to 40 of about 20,624 (255)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Entropy, 2015 A projective synchronization scheme for a kind of n-dimensional discrete dynamical system is proposed by means of a linear feedback control technique.
Baogui Xin, Zhiheng Wu
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reachability in Biochemical Dynamical Systems by Quantitative Discrete Approximation (extended abstract) [PDF]
Electronic Proceedings in Theoretical Computer Science, 2011 In this paper, a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced.
L. Brim +3 more
doaj +1 more source
Symmetries and Dynamics of Discrete Systems [PDF]
, 2007 We consider discrete dynamical systems and lattice models in statistical mechanics from the point of view of their symmetry groups. We describe a C program for symmetry analysis of discrete systems. Among other features, the program constructs and investigates phase portraits of discrete dynamical systems modulo groups of their symmetries, searches ...
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Dynamics of Nonautonomous Discrete Dynamical Systems
, 2015 In this paper we study the dynamics of a general non-autonomous dynamical system generated by a family of continuous self maps on a compact space $X$. We derive necessary and sufficient conditions for the system to exhibit complex dynamical behavior. In the process we discuss properties like transitivity, weakly mixing, topologically mixing, minimality,
Sharma, Puneet, Raghav, Manish
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
GDSCalc: A Web-Based Application for Evaluating Discrete Graph Dynamical Systems.
PLoS ONE, 2015 Discrete dynamical systems are used to model various realistic systems in network science, from social unrest in human populations to regulation in biological networks.
Sherif H Elmeligy Abdelhamid +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source