Results 21 to 30 of about 36,079 (260)

Enhancing Construction Process Employing Lean Principles and Discrete Event Simulation [PDF]

open access: yesمهندسی عمران شریف, 2021
Traditional push-based planning systems often result in several types of waste due to mainly improper distribution of resources. Waste may have several adverse effects on a project, including the increases in cost, duration, and emission.
kh. Aseyedesmaeili   +2 more
doaj   +1 more source

Towards a DEVS Model Management System for Decision-Making Web Applications

open access: yesInformation, 2023
The discrete event system specification formalism introduced by Zeigler in the 1970s is ideally associated with new technological advances in the web to offer an almost quasi-automatic mechanism for exporting its simulation models associated with ...
Laurent Capocchi   +1 more
doaj   +1 more source

Discrete event simulation in Pascal with SIMTOOLS [PDF]

open access: yesProceedings of the 18th conference on Winter simulation - WSC '86, 1986
In recent years a great deal of research effort has been devoted to improving simulation software. Products currently available for discrete event simulation include GPSS/H, SIMSCRIPT II.5, SIMULA, SLAM, SIMAN, SIMPAS, PASSIM, and ASSE, to name a few. Some of these products (SIMSCRIPT II.5 and SIMPAS, for example) use process-oriented approaches.
openaire   +2 more sources

Discrete Event Simulation of Hybrid Systems [PDF]

open access: yesSIAM Journal on Scientific Computing, 2004
Summary: This paper describes the quantization-based integration methods and extends their use to the simulation of hybrid systems. Using the fact that these methods approximate ordinary differential equations (ODEs) and differential algebraic equations (DAEs) by discrete event systems, it is shown how hybrid systems can be approximated by pure ...
openaire   +3 more sources

A dilemma study of the traffic flow system emerged due to the lane-change by follower’s tailgating effect

open access: yesScientific Reports
In this study, an artificial traffic system, which is generated on a computer by utilizing the computational technique, has been developed by establishing brilliant lane-changing criteria for the Cellular Automata (CA) traffic model to figure out ...
Fumi Sueyoshi   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Human factors in an automotive discrete event simulation model

open access: yesActa Scientiarum: Technology, 2017
Human beings have naturally different variations in performance which may lead towards significant differences between the results forecasted by simulation models and those actually obtained.
Rafael de Carvalho Miranda   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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