Results 51 to 60 of about 87,788 (265)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Discrete event control of nondeterministic systems

Proceedings of 35th IEEE Conference on Decision and Control, 1998
Summary: Nondeterminism in discrete-event systems occurs in many practical situations and often as a result of partial observability of events. For the adequate description of nondeterministic systems and nondeterministic phenomena, the trajectory-model formalism was introduced. This formalism has been used in [\textit{M. Shayman} and \textit{R. Kumar},
Michael Heymann, Feng Lin
openaire   +2 more sources

Event-Based Modeling of Input Signal Behaviors for Discrete-Event Controllers

Applied Sciences
Controllers for discrete-event systems are commonly designed using state-based formalisms, like state diagrams and Petri nets. These formalisms are strongly supported by the concept of events, which, from an automation system perspective, can be ...
Luis Gomes, Diogo Natário, Anikó Costa, João-Paulo Barros, Rogério Campos-Rebelo   +4 more
doaj   +1 more source

Commissioning of a production line in the discrete event simulation software Ururau

GEPROS: Gestão da Produção, Operações e Sistemas, 2017
The aim of this work was to demonstrate the utilization of a discrete event simulation model built with the Ururau software integrated to a programmable logic controller to be applied in commissioning of control systems.
Quézia Manuela Gonçalves Laurindo, João José de Assis Rangel, Túlio Almeida Peixoto, Eder Reis Tavares, Fábio Freitas da Silva, Ítalo de Oliveira Matias   +5 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Calculating Restart States for Systems Modeled by Operations Using Supervisory Control Theory

Machines, 2013
This paper presents a supervisory control theory based offline method for calculating restart states in a manufacturing control system. Given these precalculated restart states, an operator can be given correct instructions for how to resynchronize the ...
Patrik Bergagård, Martin Fabian
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

A discrete event model for real time system simulation

Journal of Computer Science and Technology, 2012
In this work we present a discrete event model to design and implement a real time system simulator. This kind of software is useful to verify and evaluate algorithms and models, and to compute performance metrics. The discrete event model fits perfectly
Francisco E. Páez, José M. Urriza, Carlos Buckle, Lucas Schorb, Javier D. Orozco   +4 more
doaj