Results 71 to 80 of about 5,162,641 (303)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Simulation study for investment decisions on the EcoBoost camshaft machining line [PDF]

, 2011
Design/redesign of manufacturing systems is a complex, risky, and expensive task. Ford Motor Company’s Valencia Engine Plant faces this challenge as it plans to upgrade its machining and assembly lines to introduce the new EcoBoost engines.
de Sanabria Sales, R. R., B Tjahjono, A G de Rueda, C Temple, Ladbrook, J., Tjahjono, Benny, de Rueda, A. G., Oakes, E., R R de Sanabria Sales, U Lizarazu, Lizarazu, U., Temple, Clive, E Oakes, J Ladbrook   +13 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Reducing auto moiré in discrete line juxtaposed halftoning [PDF]

, 2013
Discrete line juxtaposed halftoning creates color halftones with discrete colorant lines of freely selectable rational thicknesses laid-out side by side.
Roger D. Hersch, Vahid Babaei, Babaei, Vahid, Hersch, Roger   +3 more
core   +2 more sources

A Generalized Voronoi Diagram-Based Segment-Point Cyclic Line Segment Matching Method for Stereo Satellite Images

Remote Sensing
Matched line segments are crucial geometric elements for reconstructing the desired 3D structure in stereo satellite imagery, owing to their advantages in spatial representation, complex shape description, and geometric computation.
Li Zhao, Fengcheng Guo, Yi Zhu, Haiyan Wang, Bingqian Zhou   +4 more
doaj   +1 more source

Design and Implementation of Discrete Multitone Modulator for Digital Subscriber Line Using FPGA [PDF]

Engineering and Technology Journal, 2014
This paper presents a design, simulation and implementation of the Discrete Multitone (DMT) modulator for digital subscriber line (DSL) for both complex and real transmission based on Software Defined Radio (SDR) using FPGA.
Hadi T. Ziboon, Ikhlas M. Farhan
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Discrete Wavelet Multi-Tone Transmission for Digital Subscriber Line

Journal of Engineering and Sustainable Development, 2005
Multi-Carrier Modulation (MCM) is an attractive technique for copper wire access technology in high-performance communication networks (e.g. Asymmetric and Very-high-rate Digital Subscriber Line). In digital implementations of MCM, subcarrier generation
Abdul-Karim Abdul-Rahman Kadhim
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Supervision equivalence [PDF]

, 2006
This paper presents a general framework for modular synthesis of supervisors for discrete event systems. The approach is based on compositional minimisation, using concepts of process equivalence.
Hugo Flordal, Flordal, Hugo, Malik, Robi, Robi Malik   +3 more
core   +1 more source