Results 51 to 60 of about 5,162,641 (303)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Unique positive solution for an alternative discrete Painlevé I equation [PDF]

open access: yes, 2016
We show that the alternative discrete Painleve I equation has a unique solution which remains positive for all n >0. Furthermore, we identify this positive solution in terms of a special solution of the second Painleve equation involving the Airy ...
Clarkson, Peter   +4 more
core   +1 more source

Digital Twin-Driven Multi-Factor Production Capacity Prediction for Discrete Manufacturing Workshop

open access: yesApplied Sciences
Traditional capacity forecasting algorithms lack effective data interaction, leading to a disconnection between the actual plan and production. This paper discusses the multi-factor model based on a discrete manufacturing workshop and proposes a digital ...
Hu Cai, Jiafu Wan, Baotong Chen
doaj   +1 more source

Abundant traveling wave solutions to an intrinsic fractional discrete nonlinear electrical transmission line

open access: yesResults in Physics, 2021
The main idea of this paper is to search for all traveling wave solutions to an intrinsic fractional discrete nonlinear electrical transmission line, which plays a essential role in obtaining the new insights in nonlinear voltage dynamics.
Shuangqing Chen   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Discrete Exterior Calculus [PDF]

open access: yes, 2003
This thesis presents the beginnings of a theory of discrete exterior calculus (DEC). Our approach is to develop DEC using only discrete combinatorial and geometric operations on a simplicial complex and its geometric dual.
Hirani, Anil Nirmal
core   +1 more source

The Discrete and Continuum Broken Line Process

open access: yes, 2009
In this work we introduce the discrete-space broken line process (with discrete and continues parameter values) and derive some of its properties. We explore polygonal Markov fields techniques developed by Arak-Surgailis. The discrete version is presented first and a natural continuum generalization to a continuous object living on the discrete lattice
L. Rolla   +3 more
openaire   +3 more sources

The Discrete Resource Allocation Problem in Flow Lines [PDF]

open access: yesManagement Science, 1995
In this paper we address the discrete resource allocation problem in a deterministic flow line. We assume that the processing times are convex and nonincreasing in the amount of resources allocated to the machines. We consider the resource allocation problem for a fixed sequence of jobs for various performance criteria (makespan, weighted sum of ...
Selcuk Karabati   +2 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Relaxation of thermal stress by dislocation motion in passivated metal interconnects [PDF]

open access: yes, 2004
The development and relaxation of stress in metal interconnects strained by their surroundings (substrate and passivation layers) is predicted by a discrete dislocation analysis.
Giessen, Erik van der,   +9 more
core   +2 more sources

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