Results 141 to 150 of about 199,846 (198)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

open access: yesAdvanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang   +12 more
wiley   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

A decision support tool for the location, districting and dimensioning of Community Health Houses. [PDF]

open access: yesHealth Care Manag Sci
Doneda M   +6 more
europepmc   +1 more source

Multifunctional Programmable Transmissive Metasurface with Phase and Amplitude Manipulation Capability

open access: yesAdvanced Science, EarlyView.
This work provides a multifunctional programmable transmissive metasurface with phase and amplitude manipulation capability in the sub‐6G band. By applying different coding strategies, the proposed metasurface can realize vortex beam generation, holographic imaging under phase coding mode, and multi‐beam forming in phase‐amplitude joint coding mode ...
Hao Tian Shi   +8 more
wiley   +1 more source

Trichomonas vaginalis strain diversity among female sex workers in Ecuador using DNA sequence-based typing. [PDF]

open access: yesBMC Infect Dis
Broad CE   +5 more
europepmc   +1 more source

Truncated Conjugate Structure Improves Solar‐Driven Hydrogen Peroxide Production Catalyzed by Benzobisthiazole‐Based Conjugated Polymers

open access: yesAdvanced Science, EarlyView.
In this work, a novel molecular design strategy was employed to truncate large‐scale conjugated structures in covalent polymer materials. This approach significantly enhances the catalyst’s light‐harvesting capability, prolongs the lifetime of photogenerated charge carriers, and improves catalytic activity, thereby offering a new conceptual pathway for
Cui Li   +4 more
wiley   +1 more source

Unveiling a Stable Polysulfide Transport Framework in a Fluorine‐Free Li‐S Batteries

open access: yesAdvanced Science, EarlyView.
This work unveils a lithium thiophosphate reaction pathway activated by trigger P2S5 units, which initiate fast self‐assembly and shift the system away from conventional Li‐S reactions. The reversible Li‐P‐S framework delivers stability, safety, and high energy density, while enabling a distinct solid‐liquid hybrid electrochemical mode that provides a ...
Feng‐Yu Wu   +3 more
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

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