Results 161 to 170 of about 1,119,408 (283)

Customizing Tactile Sensors via Machine Learning‐Driven Inverse Design

open access: yesAdvanced Science, EarlyView.
ABSTRACT Replicating the sophisticated sense of touch in artificial systems requires tactile sensors with precisely tailored properties. However, manually navigating the complex microstructure‐property relationship results in inefficient and suboptimal designs.
Baocheng Wang   +15 more
wiley   +1 more source

Annealing‐Induced Plasticity and Strengthening in Metallic Glasses

open access: yesAdvanced Science, EarlyView.
This work challenges the dogma that annealing inevitably embrittles metallic glasses. We demonstrate that sub‐Tg annealing, guided by positive mixing enthalpy and constrained kinetics, can drive a self‐organized compositional fluctuation that creates an interface‐free heterogeneous structure.
Yingjie Zhang   +17 more
wiley   +1 more source

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

open access: yesAdvanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su   +7 more
wiley   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

open access: yesAdvanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong   +21 more
wiley   +1 more source

Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing

open access: yesAdvanced Science, EarlyView.
The critical pore spacing—approximately twenty times the pore radius—required to minimize electric field coupling is determined via finite element analysis. A multi‐layered Al2O3/Au/Si3N4 nanopore structure fabricated by helium ion beam lithography is proposed, enabling quantitative analysis of the target analyte while mitigating inter‐pore crosstalk ...
Silu Feng   +5 more
wiley   +1 more source

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