Results 51 to 60 of about 846,444 (289)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

On the Power of Conditional Samples in Distribution Testing [PDF]

open access: yes, 2013
In this paper we define and examine the power of the {\em conditional-sampling} oracle in the context of distribution-property testing. The conditional-sampling oracle for a discrete distribution $\mu$ takes as input a subset $S \subset [n]$ of the ...
Chakraborty, Sourav   +3 more
core   +2 more sources

Sampling and Discrete Linear Canonical Transforms [PDF]

open access: yes, 2016
A discrete linear canonical transform would facilitate numerical calculations in many applications in signal processing, scalar wave optics, and nuclear physics. The question is how to define a discrete transform so that it not only approximates the continuous transform well, but also constitutes a discrete transform in its own right, being complete ...
Healy J.J., Ozaktas H.M.
openaire   +4 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Approximate Nonlinear Discrete-Time Models Based on B-Spline Functions

open access: yesIEEE Access, 2020
We consider the discretization of continuous-time nonlinear systems described by normal forms. In particular, we consider the case when the input to the system is generated by a B-spline hold device to obtain an approximate discrete-time model.
Claudia Sanchez, Juan I. Yuz
doaj   +1 more source

Some considerations on aggregate sample supports for soil inventory and monitoring [PDF]

open access: yes, 2012
Soil monitoring and inventory require a sampling strategy. One component of this strategy is the support of the basic soil observation: the size and shape of the volume of material that is collected and then analysed to return a single soil datum.
Arrouays   +20 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Exactness and Ordering in Discrete Cavalieri Sampling

open access: yesImage Analysis and Stereology
We study the discrete Cavalieri estimator under systematic sampling from a finite population, which models an object represented by a finite sequence of blocks along a sampling axis.
Francisco Javier Soto Sánchez
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Theory of Sampling for Continuous-time Metric Temporal Logic

open access: yes, 2009
This paper revisits the classical notion of sampling in the setting of real-time temporal logics for the modeling and analysis of systems. The relationship between the satisfiability of Metric Temporal Logic (MTL) formulas over continuous-time models and
Asarin E.   +24 more
core   +3 more sources

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