Results 201 to 210 of about 850,977 (257)

A guide to transient absorption spectroscopy for porous crystalline materials in photocatalysis. [PDF]

Nat Commun
King AJ, Chen L, Maurer AB, Huang J.
europepmc   +1 more source

Chemoproteomic discovery of a brain‐penetrant, covalent NLRP3 inhibitor that binds a novel allosteric pocket

British Journal of Pharmacology, EarlyView.
NLRP3 is a promising inflammatory target, but existing inhibitors lack diversity and brain penetrance, and none are approved. Using chemoproteomics, we discovered a novel series that binds to Cys463 in a previously uncharacterized pocket. Compounds showed nanomolar potency, brain exposure, and in vivo suppression of IL‐1β, supporting neuroinflammatory ...
Donald C. Rogness, Evelyn P. Sievert, Vincent F. Vartabedian, Steffen M. Bernard, Erick Aitchison, William Tao, Mikaela Lindvall, Jing Qian, Christie L. Eissler, Brian E. Nordin, Benjamin D. Horning, Cian Kingston, Kelsey N. Lamb, Joshua C. Bell, Bingwen Lu, Jonathan Pollock, Jun Shi, Roli Khattri, David S. Weinstein, Matthew P. Patricelli, Brian N. Cook, Gabriel M. Simon   +21 more
wiley   +1 more source

Exploring Quantum-Inspired Encoding Strategies in Neuromorphic Systems for Affective State Recognition. [PDF]

Sensors (Basel)
Wang F, Liang X, Du X.
europepmc   +1 more source

Enhancing lung cancer classification through a double attention hybrid CNN-HiFuse approach. [PDF]

Sci Rep
M D A, B V.
europepmc   +1 more source

Singular effect of linkage on long-term genetic gain in Fisher's infinitesimal model. [PDF]

PNAS Nexus
Tourrette E, Martin OC.
europepmc   +1 more source

Research and Implementation of Localization of Multiple Local Discharge Sources in Switchgear Based on Ultrasound. [PDF]

Sensors (Basel)
Xu D, Huang Y, Mitra AD, Yang SX, Li P, Xiao M, Su L, Song L.   +7 more
europepmc   +1 more source

End-to-End Interrupted Sampling Repeater Jamming Countermeasure Network Under Low Signal-to-Noise Ratio. [PDF]

Sensors (Basel)
Dai G, Yang X, Huan S, Chen Z, Peng C, Xu Y.   +5 more
europepmc   +1 more source

An enhanced adaptive image steganography method using block skin-maps and the integer S-transform. [PDF]

Sci Rep
Khalifa A, Khafaga DS, Sadek M, Aldakheel EA.   +3 more
europepmc   +1 more source

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Discrete singular convolution for beam analysis

Engineering Structures, 2001
This paper explores the utility of a discrete singular convolution (DSC) algorithm for beam analysis. Regularized Shannon and Dirichlet kernels are selected to illustrate the present algorithm. Three classes of benchmark beam problems, including bending, vibration and buckling, are utilized to test numerical accuracy and speed of convergence of the ...
G W Wei
openaire   +3 more sources

Discrete singular convolution for buckling analyses of plates and columns

Structural Engineering and Mechanics, 2008
In the present study, the discrete singular convolution (DSC) method is developed for buckling analysis of columns and thin plates having different geometries. Regularized Shannon?s delta (RSD) kernel is selected as singular convolution to illustrate the present algorithm.
Civalek, Ömer, Yavaş, Altuğ
openaire   +5 more sources