Results 51 to 60 of about 2,171,485 (241)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
The Ziegler spectrum for derived-discrete algebras [PDF]
, 2017 Let Λ be a derived-discrete algebra. We show that the Krull–Gabriel dimension of the homotopy category of projective Λ-modules, and therefore the Cantor–Bendixson rank of its Ziegler spectrum, is 2, thus extending a result of Bobiński and Krause [8].
Laking, Rosanna +3 more
core +4 more sources
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Schrödinger Operators with Purely Discrete Spectrum [PDF]
, 2009 We prove that −Δ+V has purely discrete spectrum if V ≥ 0 and, for all M, |{x | V (x)
Simon, B.
core +2 more sources
Non-Distorted Optimization Spectrum Analysis
Energies, 2018 The discrete Fourier transform is extensively applied in spectrum analysis. However, the sampled signal is random, and the discrete Fourier transform has its own specific limitations.
Rong-Ching Wu, Li-Ju Huang
doaj +1 more source
Ergodic measure preserving transformations with quasi-discrete spectrum
, 1974 It is shown that an ergodic measure preserving transformation with quasi-discrete spectrum is conjugate to: (a) the skew-product of an ergodic measure preserving transformation with discrete spectrum and a measurable family of totally ergodic measure ...
James B. Robertson
core +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
The Energy Spectrum of the Acoustic Emission Signals of Nanoscale Objects [PDF]
Журнал нано- та електронної фізики, 2017 A one-dimensional discrete-continuum model of the energy spectrum of the acoustic emission signal, allowing filter oscillating components of the acoustic emission signals.
V.V. Marasanov, A.A. Sharko
doaj +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source