Results 81 to 90 of about 996,158 (312)
Advanced Science, EarlyView.This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang +10 more
wiley +1 more source
Minimal scoto-seesaw mechanism with spontaneous CP violation
Journal of High Energy Physics, 2021 We propose simple scoto-seesaw models to account for dark matter and neutrino masses with spontaneous CP violation. This is achieved with a single horizontal Z 8 $$ {\mathcal{Z}}_8 $$ discrete symmetry, broken to a residual Z 2 $$ {\mathcal{Z}}_2 ...
D. M. Barreiros +3 more
doaj +1 more source
Advanced Science, EarlyView.4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang +19 more
wiley +1 more source
Advanced Science, EarlyView.Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
wiley +1 more source
Every group is a maximal subgroup of the free idempotent generated semigroup over a band [PDF]
, 2013 Given an arbitrary group G we construct a semigroup of idempotents (band) BG with the property that the free idempotent generated semigroup over BG has a maximal subgroup isomorphic to G. If G is finitely presented then BG is finite. This answers several
Ruskuc, Nik +3 more
core +1 more source
A Thickness‐Invariant Origami Robot With Integrated Actuation and Multimodal Locomotion
Advanced Science, EarlyView.A thickness‐invariant variation on the Yoshimura origami pattern is used as the basis of a robot, allowing power, actuation, and control systems to be embedded within the thickened panels of the pattern. The robot uses multiple kinematic branches to achieve distinct modes of locomotion, such as walking, running, galloping, and turning. ABSTRACT Origami
Davis Wing +4 more
wiley +1 more source
Quark mixing from Δ(6N2) family symmetry
Physics Letters B, 2015 We consider a direct approach to quark mixing based on the discrete family symmetry Δ(6N2) in which the Cabibbo angle is determined by a residual Z2×Z2 subgroup to be |Vus|=0.222521, for N being a multiple of 7.
Hajime Ishimori +3 more
doaj +1 more source
Subgroup separability, knot groups, and graph manifolds
, 2000 This paper answers a question of Burns, Karrass and Solitar by giving examples of knot and link groups which are not subgroup-separable. For instance, it is shown that the fundamental group of the square knot complement is not subgroup separable.
Wise, Daniel T. +3 more
core
Multiplicative Invariants and the Finite Co-Hopfian Property [PDF]
, 2009 A group is said to be, finitely co-Hopfian when it contains no proper subgroup of finite index isomorphic to itself. It is known that irreducible lattices in semisimple Lie groups are finitely co-Hopfian.
Humphreys, JJAM, Johnson, FEA
core
Advanced Science, EarlyView.TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin +10 more
wiley +1 more source