Results 31 to 40 of about 285,369 (255)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Positivity of Fractional Descriptor Linear Discrete–Time Systems
International Journal of Applied Mathematics and Computer Science, 2019 The positivity of fractional descriptor linear discrete-time systems is investigated. The solution to the state equation of the systems is derived. Necessary and sufficient conditions for the positivity of fractional descriptor linear discrete-time ...
Kaczorek Tadeusz
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Convergence time towards periodic orbits in discrete dynamical systems. [PDF]
PLoS ONE, 2014 We investigate the convergence towards periodic orbits in discrete dynamical systems. We examine the probability that a randomly chosen point converges to a particular neighborhood of a periodic orbit in a fixed number of iterations, and we use ...
Jesús San Martín, Mason A Porter
doaj +1 more source
Discrete-time negative imaginary systems [PDF]
Automatica, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ferrante, A. +2 more
openaire +2 more sources
Synchronization in Discrete-Time, Discrete-State Random Dynamical Systems [PDF]
SIAM Journal on Applied Dynamical Systems, 2020 18 pages, 3 ...
Huang, Wen +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Guaranteed cost stabilization control of discrete‐time switched systems
IET Control Theory & Applications, 2021 This paper is concerned with the guaranteed cost control problem of a class of linear discrete‐time switched systems with parametric uncertainties. Both state‐based and dynamic output‐based robust stabilization problems are investigated by using mode ...
Shengli Du +3 more
doaj +1 more source