Results 121 to 130 of about 2,890,899 (238)

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Discretionary Compromises: How Clinicians Navigate Competing Values in Cardiovascular Patient Prioritisation. [PDF]

Sociol Health Illn
Teig IL, Andvik E.
europepmc   +1 more source

Effect of esomeprazole on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader, in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study is to evaluate the effects of multiple doses of esomeprazole, a strong proton pump inhibitor and acid‐reducing agent, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader.
Lana Tran, Naihan Chen, Jennifer A. Winton, Kyle T. Matschke, Smita P. Goodman, Kimberly C. Lee, Yuanyuan Zhang, Weiwei Tan   +7 more
wiley   +1 more source

Beyond pharmaceutical bandaids: universal access to antiretroviral therapy in Canada. [PDF]

CMAJ
Brisson J, Sheehan N, Lemire B, Monteith K, David PM.   +4 more
europepmc   +1 more source

Cefepime exposure in prolonged or intermittent infusion in critically ill children

British Journal of Clinical Pharmacology, EarlyView.
Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient.
Marc Hobeika, Deborah Hirt, Emmanuelle Bille, Sihem Benaboud, Julie Toubiana, Pierre‐Louis Léger, Jérôme Rambaud, Agathe Béranger, Delphine Callot, Sylvain Renolleau, Jean‐Marc Treluyer, Mehdi Oualha, Noémie de Cacqueray   +12 more
wiley   +1 more source

Parental Decision-Related Factors Are Associated with Discretionary Ultra-Processed Food Consumption Among Children and Adolescents Living in the Mediterranean Area. [PDF]

Nutrients
Giampieri F, Leonardi A, Di Costanzo G, Abril-Mera T, Rosi A, Frias-Toral E, Ammar A, Zambrano-Villacres R, Abdelkarim O, Aly M, Pons J, Vázquez-Araújo L, Maniega Legarda F, Scuderi A, Decembrino N, Mata A, Chacón A, Busó P, Galvano F, Bonaccio M, Grosso G.   +20 more
europepmc   +1 more source

THE COLLABORATIVE MODEL TO SUPPORT DISCRETIONARY DECISION-MAKING IN E-GOVERNMENT

, 2008
Good governance is the ultimate goal of e-government in an information society. Discretionary powers of administrative officials are often viewed as a major obstacle to good governance in which bureaucratic decisions may be made by whim, caprice, chance,

core  

Framing National Education in Hong Kong: A frame analysis of power dynamics in stakeholders' competing narratives

British Educational Research Journal, EarlyView.
Abstract This article examines how national education in Hong Kong functions as a contested arena in which state and non‐state actors struggle over the meaning of citizenship, identity and schooling. Using inductive frame analysis of 319 news articles (2020–2025) from five Chinese‐ and English‐language outlets, it identifies diagnostic, prognostic and ...
Jason Cong Lin
wiley   +1 more source

Antimicrobial stewardship in hospitals: effective and indispensable, yet structurally fragile. [PDF]

Front Public Health
Zavaleta-Monestel E, Mosmann-Menezes R, Mora-Jiménez J, Arguedas-Chacón S, Diaz-Madriz JP.   +4 more
europepmc   +1 more source

Publicly funded private schools and academic achievement: A comparative analysis of PISA data in European countries

British Educational Research Journal, EarlyView.
Abstract This paper analyses differences in academic achievement associated with attendance at publicly funded private schools and public schools across 11 European countries. Using eight waves of PISA data (2000–2022), we apply OLS, IPW and IPWRA estimators to account for observed heterogeneity and mitigate selection bias.
Priya Maurya, Léonard Moulin, Denis Fougère   +2 more
wiley   +1 more source