Results 31 to 40 of about 569,150 (248)

Pattern discrimination

open access: yes, 2018
How do “human” prejudices reemerge in algorithmic cultures allegedly devised to be blind to them? To answer this question, this book investigates a fundamental axiom in computer science: pattern discrimination. By imposing identity on input data, in order to filter—that is, to discriminate—signals from noise, patterns become a highly political issue ...
Apprich, Clemens   +3 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Racism in German healthcare: uncovering the construction and silencing of the “other”

open access: yesFrontiers in Public Health
While the impact of racism on healthcare interactions has been researched extensively in many parts of the world, substantive studies on healthcare-related racism in Europe, and particularly in Germany, remain scarce.
Tanja Gangarova   +2 more
doaj   +1 more source

Le racisme systémique et son cadre racial blanc : une perspective critique

open access: yesSocio, 2023
L’histoire nationale américaine a été largement mythifiée : a contrario de l’image d’un pays de liberté et de justice, les États-Unis ont en réalité fondé leur développement économique d’abord sur l’esclavage racialisé, ensuite sur la ségrégation raciale.
Joe R. Feagin
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

NATIONAL COUNCIL FOR COMBATING DISCRIMINATION – COURT OF JUSTICE OF EUROPEAN UNION – BUCHAREST COURT OF APPEAL. CAUSE C-81/12 [PDF]

open access: yesChallenges of the Knowledge Society, 2014
The scope of this investigation consists in closing the jurisdictional circle initiated in 2010 and analysing the national and European procedural, jurisdictional-administrative issues, in case of notifying some institutions related to certain ...
Cristian JURA
doaj  

Investigation of the Causes of Negative Attitudes towards Women Incompatible with Gender Stereotypes within the Context of Social Identity Theory

open access: yesPsikiyatride Güncel Yaklaşımlar, 2023
The primary gender stereotypes accepted in mainstream social psychology describe women as low in competence and high in warmth, men as having low warmth and high competence.
Ezgi Kaşdarma
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

FROM THE NATIONAL COUNCIL FOR COMBATING DISCRIMINATION TO THE COURT OF JUSTICE OF EUROPEAN UNION – CASE C-81/12 [PDF]

open access: yesChallenges of the Knowledge Society, 2013
The scope of this research is to present and analyze national and European, jurisdictional-administrative procedural issues, if courts are notified related to certain discriminatory statements.
CRISTIAN JURA
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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