Results 41 to 50 of about 601,087 (267)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

“The Best Times of Our Lives?” Institutional Factors That Shape University Students’ Quality of Life

SAGE Open
Acquiring a thorough grasp of the factors influencing students’ academic quality of life is essential for educators, administrators, and legislators to successfully support students and foster an environment centered on their well-being and growth ...
Atalia Oniţiu, Elena-Loreni Baciu, Theofild-Andrei Lazăr, Roxana Ungureanu, Loredana-Marcela Trancă, Norberth-Ioan Okros   +5 more
doaj   +1 more source

Evaluating student evaluations: evidence of gender bias against women in higher education based on perceived learning and instructor personality

Frontiers in Education, 2023
Given student evaluations are an integral part of academic employment and progression in higher education, it is crucial to explore various biases amongst students that may influence their ratings.
Olga Khokhlova, Nishtha Lamba, Sameer Kishore   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Racism in German healthcare: uncovering the construction and silencing of the “other”

Frontiers in Public Health
While the impact of racism on healthcare interactions has been researched extensively in many parts of the world, substantive studies on healthcare-related racism in Europe, and particularly in Germany, remain scarce.
Tanja Gangarova, Melike Yildiz, Lina Kabangu   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

NATIONAL COUNCIL FOR COMBATING DISCRIMINATION – COURT OF JUSTICE OF EUROPEAN UNION – BUCHAREST COURT OF APPEAL. CAUSE C-81/12 [PDF]

Challenges of the Knowledge Society, 2014
The scope of this investigation consists in closing the jurisdictional circle initiated in 2010 and analysing the national and European procedural, jurisdictional-administrative issues, in case of notifying some institutions related to certain ...
Cristian JURA
doaj  

From Sintering to Particle Discrimination: New Opportunities in Metal–Organic Frameworks Scintillators

Advanced Photonics Research, 2022
The characterization of a scintillating metal organic framework (MOF) is not straightforward, mainly due to the small size and low density of the material. In this context, we present herein a generic method to give an easy access to the determination of
Vincent Villemot, Nicolas Dufour, Sharvanee Mauree, Benoît Sabot, Guillaume H. V. Bertrand, Matthieu Hamel   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

FROM THE NATIONAL COUNCIL FOR COMBATING DISCRIMINATION TO THE COURT OF JUSTICE OF EUROPEAN UNION – CASE C-81/12 [PDF]

Challenges of the Knowledge Society, 2013
The scope of this research is to present and analyze national and European, jurisdictional-administrative procedural issues, if courts are notified related to certain discriminatory statements.
CRISTIAN JURA
doaj