Results 81 to 90 of about 197,777 (277)

Speech Sound Discrimination Ability in Young Children

open access: yesAUDIOLOGY JAPAN, 1976
In order to examine children's auditory discrimination ability of speech sounds, the results of two popular methods were compared.The subjects were 59 of 4-year-old and 33 of 5 year-old children whose articulation of /t/, /k/, and /t∫/ sounds were normal, and their ability to discriminate these sounds was supposed to be normal.All speech sound used as ...
Shigetada Suzuki   +4 more
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

An integrated machine learning-based model for joint diagnosis of ovarian cancer with multiple test indicators

open access: yesJournal of Ovarian Research
Objective To construct a machine learning diagnostic model integrating feature dimensionality reduction techniques and artificial neural network classifiers to develop the value of clinical routine blood indexes for the auxiliary diagnosis of ovarian ...
Yiwen Feng
doaj   +1 more source

Compact Dominant Synergistic Excitation Pattern Learning for Illumination-Insensitive Image Representation With Boosting

open access: yesIEEE Access, 2019
Illumination-insensitive image representation is a great challenge in the computer vision field. Illumination variations considerably obstruct the effectiveness of image feature extraction.
Tao Gao   +5 more
doaj   +1 more source

Distribution Shift Metric Learning for Fine-Grained Ship Classification in SAR Images

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
Fine-grained ship classification in synthetic aperture radar (SAR) images is a challenging task, since SAR images can only provide limited discriminative information due to the limitation of SAR imaging mechanism.
Yongjie Xu, Haitao Lang
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Evaluation of serum MMP-2 and MMP-3, synovial fluid IL-8, MCP-1, and KC concentrations as biomarkers of stifle osteoarthritis associated with naturally occurring cranial cruciate ligament rupture in dogs.

open access: yesPLoS ONE, 2020
The purpose of this study was to evaluate matrix metalloproteinases (MMP) -2 and MMP-3 in serum, and keratinocyte-derived chemoattractant (KC), interleukin 8 (IL-8) and monocyte chemoattractant 1 (MCP-1) in synovial fluid (SF) as stifle osteoarthritis ...
Sarah Malek   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Discriminative Autoencoding Framework for Simple and Efficient Anomaly Detection

open access: yesIEEE Access, 2019
In this paper, a discriminative autoencoding framework is proposed for semi-supervised anomaly detection using reconstruction errors. The framework only consists of a generator and a discriminative encoder, and the output of the latter is a vector.
Sheng Mao, Jiansheng Guo, Zhengxin Li
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

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