Results 141 to 150 of about 11,523,117 (237)
, 2016 This is the second consultation document for the Elder Abuse Inquiry, in which the ALRC has been asked to consider existing Commonwealth laws and frameworks which seek to safeguard and protect older persons from misuse or abuse by formal and informal ...
Australian Law Reform Commission
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Cancer history, rural residence, and genetic cancer risk testing engagement among U.S. adults. [PDF]
Cancer Causes ControlLee M, Zhang D, Tsai MH.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Analytical discussion of aspect, part 2
, 2016 Recording of a discussion at the 2016 Orthography Workshop at Don Bosco, Assam.Lamkang discussant are Tholung Swamy Ksen, Donnu Sankhil, Sumshot Khular, Rengpu Rex Khullar, and linguist in conversant are David A.
Chelliah, Shobhana Lakshmi
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'To Hear and Be Heard': The Co-Design of a Website to Support Communication Challenges Experienced by People With Parkinson's and Their Families and Friends. [PDF]
Int J Lang Commun DisordCocks N +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Transcription: Discussion of Laa kthee
, 2017 Transcription of a discussion of traditional songs by Shetwor Dilbung and Bunghon Suungnem at a storytelling festival funded by the NSF project and organized and implemented by Rex Khullar and Harimohon Thounaojam. The speakers discuss the types of songs
Khular, Sumshot +1 more
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