Results 141 to 150 of about 10,142,751 (308)

Disease-free survival analysis of HPV+ patients (N = 49) compared to HPV- patients (log-rank p< 0.001).

open access: yes, 2018
Disease-free survival analysis of HPV+ patients (N = 49) compared to HPV- patients (log-rank p< 0.001).
Herikson Araújo Costa (5851490)   +10 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Comparison of disease-free-survival and overall survival with respect to TP53 mutation.

open access: yes, 2014
Disease-free-survival and overall survival are not different between TP53 mutation-negative group and TP53 mutation-positive group. A and B, Disease-free-survival and overall survival in total EOC patients (n = 46, 36 TP53 mutation (−) vs.
Dae-Yeon Kim (579234)   +11 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Does the diagnostic timing of cancer-associated thromboembolism influence the survival outcome in ovarian cancer patients?

open access: yesJournal of the Formosan Medical Association
Background/Purpose: Efforts were made to explore the influence of diagnostic timing for cancer-associated thromboembolic events on survival of ovarian cancer patients.
Jung Chen   +6 more
doaj   +1 more source

Forest plot for Survival Rate: Disease-free Survival (DFS); overall survival (OS).

open access: yes, 2014
Forest plot for Survival Rate: Disease-free Survival (DFS); overall survival (OS).
Doudou Li (615434)   +11 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Survival

open access: yes, 2015
p { margin-bottom: 0.25cm; direction: ltr; line-height: 120%; text-align: left; }a:link { } Oral tongue squamous cell carcinomas (OTSCC) are a homogenous group of head and neck tumors characterized with aggressive behavior among younger age group of ...
Binay Panda (768771)
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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