Results 101 to 110 of about 26,337,030 (428)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Health Predictors of Pain in Elderly—A Serbian Population-Based Study

open access: yesDiagnostics, 2019
Objectives: The aim of our study was to evaluate the association of health factors with the presence and different degrees of pain in elderly above 65 years of life.
Milena Kostadinovic   +8 more
doaj   +1 more source

Opportunities to monitor animal welfare using the five freedoms with precision livestock management on rangelands

open access: yesFrontiers in Animal Science, 2022
Advances in technology have led to precision livestock management, a developing research field. Precision livestock management has potential to improve sustainable meat production through continuous, real-time tracking which can help livestock managers ...
Colin T. Tobin   +5 more
doaj   +1 more source

Severe Outcomes Among Patients with Coronavirus Disease 2019 (COVID-19) — United States, February 12–March 16, 2020

open access: yesMMWR. Morbidity and mortality weekly report, 2020
Globally, approximately 170,000 confirmed cases of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) have been reported, including an estimated 7,000 deaths in approximately 150 countries (1).
Centers for Disease Control and Prevention CDC COVID-19 Response Team
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

STILL'S DISEASE

open access: yesInternational Journal of Clinical Practice, 1969
George Frederic Still (1868‐1941) was one of 12 children, three of whom died in their first year of life and two later in childhood. He was brought up in Highbury, London. He obtained a scholarship to Merchant Taylor's School and then a further scholarship to Caius College, Cambridge, where he achieved a first class honours in the Classical Tripos.
openaire   +6 more sources

Welfare in Farmed Decapod Crustaceans, With Particular Reference to Penaeus vannamei

open access: yesFrontiers in Marine Science, 2022
The farming of decapod crustaceans is a key economic driver in many countries, with production reaching around 9.4 million tonnes (USD 69.3 billion) in 2018.
Amaya Albalat   +4 more
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

On Diseases of the Skin [PDF]

open access: yesThe American Journal of the Medical Sciences
6th American from the fifth and revised London edition. ; xix, [33]-694 p.
openaire   +4 more sources

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