Results 111 to 120 of about 10,181,955 (299)

Thromboinflammatory state and venous thromboembolic events in patients with coronavirus disease 2019 admitted to a non-intensive care ward: a prospective study [PDF]

, 2020
Alberto Fortini, Chiara Beltrame, Antonio Faraone, Serena Iandelli, Giacomo Zaccagnini, Aldo Lo Forte   +5 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Main Causes of Bat Mortality Obtained Through Admission to Rescue Centres

Diversity
Bats have decreasing population trends around the world, and knowledge on the causes for this decline is the first step to improving conservation and management strategies to restore their populations.
Alfonso Balmori-de la Puente, Alfonso Balmori   +1 more
doaj   +1 more source

Biomarkers for cardiovascular disease: challenges and future directions [PDF]

, 2008
Abigail May, Thomas J. Wang
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease [PDF]

, 2018
Kassiani Kytidou, Jules Beekwilder, Marta Artola, Eline van Meel, Ruud H. P. Wilbers, Geri F. Moolenaar, Nora Goosen, María Pía Ferraz, Rebecca E. Katzy, Patrick Voskamp, Bogdan I. Florea, Cornelis H. Hokke, Herman S. Overkleeft, A. Schots, Dirk Bosch, N.S. Pannu, Johannes M. F. G. Aerts   +16 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Prevalence of fatty liver disease and its risk factors in the population of South China

, 2007
Yongjian Zhou
openalex   +1 more source

Genomic expansion of Marek's disease virus DNA is associated with serial in vitro passage [PDF]

, 1985
R F Silva, R. L. Witter
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source