Results 171 to 180 of about 27,443,428 (376)
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
ON THE CLINICAL RECOGNITION OF STRUCTURAL DISEASE OF THE PERIPHERAL VESSELS [PDF]
, 1933 George Pickering
openalex +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
DIAGNOSIS AND TREATMENT OF DISEASES OF THE THYROID GLAND [PDF]
, 1933 C George
openalex +1 more source
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
New England Journal of Medicine, 2017 M. Sabatine +11 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
New England Journal of Medicine, 2017 P. Ridker +27 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Human Disease - Unintended Globalization
, 2014 Before man was exchanging goods and ideas, he was exchanging germs. As such, the spread of infectious disease constitutes the first truly global phenomenon and, therefore, marks the beginnings—primitive though they may have been—of what today we have ...
Dellana, Christopher J.
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