Results 211 to 220 of about 26,337,030 (428)

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

open access: yesNew England Journal of Medicine, 2017
P. Ridker   +27 more
semanticscholar   +1 more source

Chagas Disease

open access: yesNeglected Tropical Diseases, 2021
Paula E. Stigler Granados   +1 more
semanticscholar   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

The Bitter Rot Disease of Apples [PDF]

open access: green, 1902
Hermann von Schrenk, Perley Spaulding
openalex   +1 more source

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

open access: yesNew England Journal of Medicine, 2017
M. Sabatine   +11 more
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Age, Serum Cholesterol and Coronary Artery Disease

open access: bronze, 1950
Menard M. Gertler   +2 more
openalex   +1 more source

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

open access: yesHepatology, 2018
N. Chalasani   +8 more
semanticscholar   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

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