Results 71 to 80 of about 26,337,030 (428)

Identifying and Exploiting Potential miRNA-Disease Associations With Neighborhood Regularized Logistic Matrix Factorization

open access: yesFrontiers in Genetics, 2018
With the rapid development of biological research, microRNAs (miRNA) have become an attractive topic because lots of experimental studies have revealed the significant associations between miRNAs and diseases.
Bin-Sheng He, Jia Qu, Qi Zhao, Qi Zhao
doaj   +1 more source

Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels [PDF]

open access: yes, 2020
Background Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn’s Disease (CD) and ulcerative colitis (UC), which causes inflammation of the gut and affects millions of people worldwide.
Alam, Mohammad T.   +5 more
core   +1 more source

Common human diseases prediction using machine learning based on survey data [PDF]

open access: yesarXiv, 2022
In this era, the moment has arrived to move away from disease as the primary emphasis of medical treatment. Although impressive, the multiple techniques that have been developed to detect the diseases. In this time, there are some types of diseases COVID-19, normal flue, migraine, lung disease, heart disease, kidney disease, diabetics, stomach disease,
arxiv  

Integrated whole transcriptome and DNA methylation analysis identifies gene networks specific to late-onset Alzheimer’s disease [PDF]

open access: yes, 2014
Previous transcriptome studies observed disrupted cellular processes in late-onset Alzheimer\u27s disease (LOAD), yet it is unclear whether these changes are specific to LOAD, or are common to general neurodegeneration.
Beecham, G.   +8 more
core   +3 more sources

Advances in the study of selenium and human intestinal bacteria

open access: yesFrontiers in Nutrition, 2022
Selenium (Se) is an essential trace element for humans and has conveyed great a wide range of interests due to its contribution to health. Presently, the regulatory mechanisms of selenium on human health, especially the regulatory mechanisms of selenium ...
Jinzhong Cai   +4 more
doaj   +1 more source

Relationship between physical activity and depression according to the presence of disease in koreans over the Age of 40 [PDF]

open access: yesCheyuk gwahag yeon-gu, 2020
Purpose The purpose of this study was to investigate the relationship between physical activity and depression according to the presence of disease. Methods A survey and basic assessment were conducted for 2,754 (Male=1,025 and Female=1,729) aged 40 and ...
Jung-woon Kim   +6 more
doaj   +1 more source

Effects of chronic browsing on life‐history traits of an irruptive large herbivore population

open access: yesPopulation Ecology, EarlyView.
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji   +9 more
wiley   +1 more source

The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]

open access: yes, 2013
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv   +1 more source

Unveiling new disease, pathway, and gene associations via multi-scale neural networks [PDF]

open access: yesPLOS ONE, 15(4), p.e0231059 (2020), 2019
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can be derived from a patient cell's profile, improving our diagnosis ability, as well as our grasp of disease risks ...
arxiv   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

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