Results 101 to 110 of about 15,873,849 (315)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
South Carolina state nutrition physical activity and obesity profile [PDF]
Many American communities lack environments that could support healthy diets and regular physical activity. Healthy dietary and physical activity practices can lower the risk for heart disease, type 2 diabetes, and some cancers.In addition, excess ...
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Oregon State Nutrition, Physical Activity, and Obesity Profile [2016] [PDF]
Many American communities lack environments that could support healthy diets and regular physical activity. Healthy dietary and physical activity practices can lower the risk for heart disease, type 2 diabetes, and some cancers.In addition, excess ...
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Pennsylvania State Nutrition, Physical Activity, and Obesity Profile [2016] [PDF]
Many American communities lack environments that could support healthy diets and regular physical activity. Healthy dietary and physical activity practices can lower the risk for heart disease, type 2 diabetes, and some cancers.1,2In addition, excess ...
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DIGESTION ACTIVITY IN MENTAL DISEASES [PDF]
The Journal of Nervous and Mental Disease, 1891 n ...
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2016 Sandra M Quezada,1 Patricia Langenberg,2 Raymond K Cross1 1Division of Gastroenterology and Hepatology, 2Division of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA Purpose: Smoking has a negative impact on ...
Langenberg P, Cross RK, Quezada SM
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Fresh Food for Health: The Impact of Onsite Produce Events at Federally Qualified Health Centers
SciThis study assessed whether frequent attendance of onsite produce events at Federally Qualified Health Centers is associated with increased fruit and vegetable consumption, reduced food insecurity, and enrollment in food assistance.
Keisha M. Macon +4 more
doaj +1 more source