Results 121 to 130 of about 13,413,197 (314)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Foodborne disease surveillance annual summary 1980
In 1980 there were 612 outbreaks (13,791 cases) of foodborne disease reported to the Centers for Disease Control. In 36% of the outbreaks, the etiology was confirmed. Bacterial pathogens accounted for 136 outbreaks (6,891 cases).
core
Fifth disease (slapped cheek syndrome)
, 2015 What is fifth disease Fifth disease, which is also known as ?slapped cheek syndrome? or erythema infectiosum is a common viral infection caused by parvovirus B19.
Centre for Disease Control
core
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Foodborne disease surveillance annual summary 1981
In 1981 there were 568 outbreaks (14,432 cases) of foodborne disease reported to the Centers for Disease Control. The etiology was confirmed in 44% of the outbreaks. Bacterial pathogens accounted for 185 outbreaks (8,208 cases).
core
, 2008 Objective: There is a general agreement that physical activity (PA) has a beneficial effecton health and those who are more active have a reduced risk of developing many chronicdiseases, such as coronary heart disease (CHD). However, the amount, type and
Al-Haifi, Ahmad
core +1 more source
BMC Public HealthMovement-related behaviors (physical activity [PA], sedentary behavior [SB], and sleep) and diet interact with each other and play important roles in health indicators in youth.
Gabrielli T. de Mello +6 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source