Results 211 to 220 of about 3,159,451 (269)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Fungal-Bacterial Dysbiosis in IBD: Microbial Biomarkers of Disease Activity. [PDF]

Microbiologyopen
Arribas-Rodríguez E, García-Pizarro M, De Prado Á, Santiago-Carretero M, Hernández M, Jiménez BV, García-Alonso J, Barrio J, Eiros JM, Arranz E, Bernardo D, Fernández-Salazar L, Cuesta-Sancho S.   +12 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Nutritional Components and Anti-Alcoholic Liver Disease Activity of Selenium-Enriched <i>Agaricus subrufescens</i>. [PDF]

Foods
Chen H, Wang Z, Zhang C, Wang S, Zeng L, Zheng F, Huang H, Deng J, Lv X, Liu P.   +9 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Patient-reported outcomes and disease activity in giant cell arteritis: a longitudinal registry-based study. [PDF]

Rheumatology (Oxford)
Skaug HK, Fevang BS, Aßmus J, Diamantopoulos AP, Myklebust G, Brekke LK.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Defining Bath Ankylosing Spondylitis Disease Activity Index Cut-off Values for Disease Activity States in a Multinational European Cohort of Patients With Axial Spondyloarthritis. [PDF]

ACR Open Rheumatol
Georgiadis S, Ørnbjerg LM, Michelsen B, Kvien TK, Shoae Kazemi M, Závada J, Pavelka K, Glintborg B, Loft AG, Reich A, Regierer AC, Rodrigues AM, Santos MJ, Rutanen J, Kuusalo L, Ciurea A, Nissen MJ, Gudbjornsson B, Pálsson Ó, Rotar Ž, Perdan Pirkmajer K, Di Giuseppe D, Østergaard M, Hetland ML.   +23 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Pregnancy Loss History Is Associated with Systemic Involvement and Disease Activity in Women with Behçet's Disease: A Retrospective Cohort Study. [PDF]

Diagnostics (Basel)
Bu R, Ma Y, Li X, Li Q, Lu L.
europepmc   +1 more source