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Assessing disease activity and disease activity indices for inflammatory bowel disease

Current Gastroenterology Reports, 2002
A crucial step in the development of clinical trials to determine the efficacy of various therapies for inflammatory bowel disease (IBD) has been the creation of activity indices. This article reviews the major components and operating characteristics of clinical activity indices commonly used in randomized, controlled trials of IBD therapy.
Feng, Xiao Li, Lloyd R, Sutherland
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Measuring disease activity in Crohn’s disease

Abdominal Imaging, 2012
In the last few years the management of Crohn's disease (CD) has changed due to the introduction of new therapeutic agents that provide more alternative options in patients with severe diseases, introducing new concepts regarding treatment timing. At the moment, the absence of good predictors of disease outcome and a subclinical marker available to ...
Onali, S   +2 more
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Measurement of Disease Activity of Pouchitis

Diseases of the Colon & Rectum, 2022
BACKGROUND:Pouchitis is the most common inflammatory complication in ulcerative colitis patients undergoing postoperative construction of an IPAA. Pouchitis refers to a spectrum of diseases, and as such, it lacks a universally accepted definition as well as validated instruments to measure disease activity and treatment response.
Roxana S, Chis, Mark S, Silverberg
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Decreased protein S activity is related to the disease activity of Behcet’s disease

Rheumatology International, 2006
We wanted to see whether the active inflammation in Behcet's disease (BD) can cause a thrombotic disorder by decreasing the protein S (PS) activity, and we evaluated the relationship between the decreased PS activity and the disease activity of BD. We included 122 patients with BD whose PS activity levels were measured.
Seong Ryul, Kwon   +4 more
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Monitoring the disease activity

Scandinavian Journal of Rheumatology, 2001
Primary Sjögren's syndrome is a chronic systemic rheumatic disease characterized as an autoimmune exocrinopathy or autoimmune epithelitis thereby suggesting a pathogenesis leading to tissue specific autoimmune lesion. The development of internationally approved criteria for the classification and diagnosis of Sjögren's syndrome has been a major ...
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The Disease Activity of Ulcerative Colitis and Crohn’s Disease

Scandinavian Journal of Gastroenterology, 1976
The disease activity in ulcerative colitis and Crohn's disease was studied. Parameters found to reflect the disease activity were given scores from 1 to 4. The score obtained by a patient compared with the maximum scores gives the percentage disease activity.
I, Talstad, E, Gjone
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Prognostic Markers of Disease Activity in Hodgkin's Disease

Leukemia & Lymphoma, 1998
The erythrocyte sedimentation rate (ESR), liver alkaline phosphatase (ALP), serum copper (Cu) and urinary nucleoside excretion (UNs) have been proposed as independent prognostic markers in Hodgkin's Disease (HD). However, their prognostic value has not satisfactorily been directly compared to recognised clinical prognostic factors.
A J, Martinow   +7 more
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Disease activity score for still’s disease

Clinical Rheumatology
To develop the Still's Disease Activity Score (SDAS).We used data from the prospective adult-onset Still's disease cohort study and evaluated the disease activity. An expert group selected the most frequent, reproducible, and objective variables significantly modified in statistical analysis when comparing patients in the active group and in the ...
Karima Daghor-Abbaci   +20 more
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