Results 241 to 250 of about 3,159,451 (269)

TESTICULAR ACTIVITY IN CUSHING'S DISEASE

Acta Endocrinologica, 1979
ABSTRACT Plasma testosterone levels were suppressed in 6 of 8 mature male patients with Cushing's disease, all of whom complained of loss of libido and decreased sexual potency. Gonadotrophin levels, both under basal conditions and in response to LH-RH, were generally normal.
T J, McKenna, D, Lorber, A, Lacroix, D, Rabin   +3 more
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Necroptosis activation in Alzheimer's disease

Nature Neuroscience, 2017
Alzheimer's disease (AD) is characterized by severe neuronal loss; however, the mechanisms by which neurons die remain elusive. Necroptosis, a programmed form of necrosis, is executed by the mixed lineage kinase domain-like (MLKL) protein, which is triggered by receptor-interactive protein kinases (RIPK) 1 and 3. We found that necroptosis was activated
Caccamo, Antonella, Branca, Caterina, Piras, Ignazio S, Ferreira, Eric, Huentelman, Matthew J, Liang, Winnie S, Readhead, Ben, Dudley, Joel T, Spangenberg, Elizabeth E, Green, Kim N, Belfiore, Ramona, Winslow, Wendy, Oddo, Salvatore   +12 more
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Lymphocyte Activation in Health and Disease

Critical Reviews in Immunology, 1997
Lymphocytes employ a complex assembly of signaling elements that have been organized on a spatiotemporal map to define their role in stimulating both proliferation and apoptosis. The antigen/major histocompatibility complex (MHC) initiates the sequence by organizing the assembly of an active T-cell receptor (TCR) complex responsible for transmitting ...
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Assessment of disease activity.

Clinical and experimental rheumatology, 2003
The objective of this study was to select a simple, feasible and validated core set of variables for the assessment of disease activity in systemic sclerosis. The subcommittee members extensively reviewed the studies in which the disease activity had been assessed, and analysed the construct validity and the feasibility of the criteria used in each ...
VALENTINI, Gabriele, SILMAN AJ, VEALE D.
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Strictureplasty for active Crohn's disease

International Journal of Colorectal Disease, 2005
Several studies over the last 20 years have confirmed the safety and efficacy of strictureplasty in the treatment of obstructive Crohn's disease. However, almost all of these studies use strictureplasty to treat fibrotic strictures: limited resection being preferred to treat active disease strictures.
Pratik, Roy, Devinder, Kumar
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Biomarkers for Disease Activity in Inflammatory Bowel Disease

Gastroenterology Clinics of North America
This summary aims to guide clinicians in applying biomarker-based monitoring strategies for personalized, evidence-based care. It provides a comprehensive update on established and emerging blood, stool, and radiological biomarkers for assessing disease activity in inflammatory bowel disease as part of a biomarker-guided treat-to-target approach ...
Jalpa, Devi, Sami, Samaan, Gaurav, Syal, Parakkal, Deepak   +3 more
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Enzyme Activity in Periodontal Disease

Journal of Periodontology, 1970
T H E EXACT ROLE that enzymes play in oral diseases has not yet been clearly defined. Various studies have been conducted to determine if salivary enzymes are asso­ ciated with high caries rates, , 2 or involved in the de­ velopment of periodontal disease.
R A, Winer, L J, O'Donnell, H H, Chauncey, T F, McNamara   +3 more
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Fibrinolytic activity in renal disease

Clinica Chimica Acta, 1972
Abstract Fibrinolytic activity in blood of thirty-three patients of renal disease was measured. The patients were divided into four groups A to D according to their renal function. Creatinine clearance values in group A (9 patients) were below 10 ml/min.
T, Ito, T, Niwa, E, Matsui
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Eosinophil Activation in Allergic Disease

International Archives of Allergy and Applied Immunology, 2009
The eosinophil granulocyte is a pro-inflammatory cell which in its granules contains an abundance of highly cytotoxic proteins such as eosinophil cationic protein, eosinophil-derived neurotoxin, eosinophil peroxidase, eosinophil protein X and major basic protein.
P, Venge, L, Håkansson, C G, Peterson
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Macrophage activation in human diseases

Seminars in Immunology, 2015
It is becoming increasingly accepted that macrophages play a crucial role in many diseases associated with chronic inflammation, including atherosclerosis, obesity, diabetes, cancer, skin diseases, and even neurodegenerative diseases. It is therefore not surprising that macrophages in human diseases have gained significant interest during the last ...
Joachim L, Schultze, Astrid, Schmieder, S, Goerdt   +2 more
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