Results 261 to 270 of about 5,766,482 (313)
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Assessing disease activity and disease activity indices for inflammatory bowel disease
Current Gastroenterology Reports, 2002A crucial step in the development of clinical trials to determine the efficacy of various therapies for inflammatory bowel disease (IBD) has been the creation of activity indices. This article reviews the major components and operating characteristics of clinical activity indices commonly used in randomized, controlled trials of IBD therapy.
Feng, Xiao Li, Lloyd R, Sutherland
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Journal of Pediatric Gastroenterology and Nutrition, 1985
Summary:Twenty‐eight patients (mean age 13.5 years) with proven Crohn's disease were examined for factor VIII coagulation activity (VIII:C), factor VIII‐related antigen (VIII R:Ag), and factor VIII‐related ristocetin cofactor activity (VIII R:RCF). The factor VIII coagulation proteins were correlated with disease activity index according to van Hees ...
S, Zielen +5 more
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Summary:Twenty‐eight patients (mean age 13.5 years) with proven Crohn's disease were examined for factor VIII coagulation activity (VIII:C), factor VIII‐related antigen (VIII R:Ag), and factor VIII‐related ristocetin cofactor activity (VIII R:RCF). The factor VIII coagulation proteins were correlated with disease activity index according to van Hees ...
S, Zielen +5 more
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Complement Activation and Cardiovascular Disease
Hormone and Metabolic Research, 2008The mechanisms by which tissue injury after acute myocardial infarction occurs have not been fully elucidated, but considerable evidence suggests that activation of complement plays an important role in the pathophysiology. Reperfusion of the ischemic myocardium is strictly necessary to rescue the exposed tissue from eventual death.
Bjerre, Mette +2 more
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Disease activity score for still’s disease
Clinical RheumatologyTo develop the Still's Disease Activity Score (SDAS).We used data from the prospective adult-onset Still's disease cohort study and evaluated the disease activity. An expert group selected the most frequent, reproducible, and objective variables significantly modified in statistical analysis when comparing patients in the active group and in the ...
Karima Daghor-Abbaci +20 more
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Monitoring the disease activity
Scandinavian Journal of Rheumatology, 2001Primary Sjögren's syndrome is a chronic systemic rheumatic disease characterized as an autoimmune exocrinopathy or autoimmune epithelitis thereby suggesting a pathogenesis leading to tissue specific autoimmune lesion. The development of internationally approved criteria for the classification and diagnosis of Sjögren's syndrome has been a major ...
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Strictureplasty for active Crohn's disease
International Journal of Colorectal Disease, 2005Several studies over the last 20 years have confirmed the safety and efficacy of strictureplasty in the treatment of obstructive Crohn's disease. However, almost all of these studies use strictureplasty to treat fibrotic strictures: limited resection being preferred to treat active disease strictures.
Pratik, Roy, Devinder, Kumar
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Necroptosis activation in Alzheimer's disease
Nature Neuroscience, 2017Alzheimer's disease (AD) is characterized by severe neuronal loss; however, the mechanisms by which neurons die remain elusive. Necroptosis, a programmed form of necrosis, is executed by the mixed lineage kinase domain-like (MLKL) protein, which is triggered by receptor-interactive protein kinases (RIPK) 1 and 3. We found that necroptosis was activated
Caccamo, Antonella +12 more
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Assessment of disease activity.
Clinical and experimental rheumatology, 2003The objective of this study was to select a simple, feasible and validated core set of variables for the assessment of disease activity in systemic sclerosis. The subcommittee members extensively reviewed the studies in which the disease activity had been assessed, and analysed the construct validity and the feasibility of the criteria used in each ...
VALENTINI, Gabriele, SILMAN AJ, VEALE D.
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Enzyme Activity in Periodontal Disease
Journal of Periodontology, 1970T H E EXACT ROLE that enzymes play in oral diseases has not yet been clearly defined. Various studies have been conducted to determine if salivary enzymes are asso ciated with high caries rates, , 2 or involved in the de velopment of periodontal disease.
R A, Winer +3 more
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The Crohn's disease activity assessment
Gastroenterology, 1998The Crohn’s disease activity ...
Ostojić, Rajko +3 more
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