Results 101 to 110 of about 821,927 (250)

Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis.

Iranian journal of medical sciences
The attentive management of rheumatoid arthritis (RA) has attracted particular attention. The German 7-joint Ultrasound (US-7) is the first scoring system that combines bone erosions and soft tissue lesions in a single composite scoring system. This study aimed to assess the correlation between US-7 and Disease Activity Score Using 28 Joint Counts ...
Ebadati, Sahar, Sahebari, Maryam, Ahmadzadeh, Amir Mahmoud, Emadzadeh, Maryam, Khoroushi, Farzaneh, Ragati Haghi, Hedieh, Giti, Ramesh, Aminzadeh, Behzad   +7 more
openaire   +3 more sources

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Translation of Rheumatoid Arthritis Disease Activity Index-5 (RADAI-5) to Punjabi Language Version and Its Correlation with Disease Activity Score 28 (DAS28) and Clinical Disease Activity Index (CDAI)

Indian Journal of Rheumatology
Introduction: Assessment of disease activity in patients with rheumatoid arthritis (RA) is usually performed using disease activity indices such as the Disease Activity Score 28 (DAS28) and the Clinical Disease Activity Index (CDAI), both of which ...
Ravreet Pal Kaur, Vikas Gupta, Sandeep Puri, Vipin Kumar   +3 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Cardiovascular risk in rheumatoid arthritis: a narrative review

Revista de la Facultad de Ciencias de la Salud, 2017
Rheumatoid arthritis (RA) is a chronic autoimmune disease with an especially articular involvement that is associated with an exponential increase in cardiovascular risk (CVR).
Manuel Felipe Cáceres Acosta, Nelson Adolfo López Garzón, Jaime Alberto Nates Burbano, Ana Isabel Ospina Caicedo   +3 more
doaj   +2 more sources

Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios Correlation with Rheumatoid Arthritis Disease Activity

Journal of Applied Hematology
BACKGROUND: Rheumatoid arthritis (RA) disease is a well-known systemic autoimmune illness typified by symmetrical polyarticular arthritis. Monitoring disease activity is essential to manage RA effectively.
Noor Hasan Baiee, Zakaria M. Al-Ghazaly, Ammar Hatem Abdullateef   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source