Results 81 to 90 of about 14,610,755 (282)

بررسی سطح سرمی ویتامین D و ارتباط آن با شدت بیماری در بیماران آرتریت روماتوئید

مجله دانشکده پزشکی اصفهان, 2017
مقدمه: آرتریت روماتوئید یک بیماری التهابی مزمن پیش‌رونده است که باعث درد و سفتی، تورم و تخریب بافت مفصل می‌شود. این مطالعه، با هدف ارزیابی رابطه‌ی سطح سرمي ويتامين D در افراد مبتلا به آرتريت روماتوئيد با شدت بیماری انجام شد.
Mohsen Noroozi, Mehdi Gholamzadeh-Baeis
doaj  

Correlation With Disease Activity Score 28 (Das28) With Pulmonary Function Test In Rheumatoid Arthritis Patients

International Journal of Research in Pharmaceutical Sciences, 2020
Rheumatoid Arthritis (RA) is a chronic inflammatory disease of unknown etiology involving both small and large joints with many extra-articular manifestations. There may be a variety of pulmonary complications associated with RA based on its disease activity and levels of RF and anti-CCP titers.
null Rameshwar R, null Srujith C. H., null Jagadeesan M, null Mahendra Kumar, null Prassana Karthik S, null Kannan R, null Magesh Kumar S, null Kavitha M. M.   +7 more
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Ultrasound Findings in Hand Joints Involvement in Patients with Psoriatic Arthritis and Its Correlation with Clinical DAS28 Score

Radiology Research and Practice, 2015
Objective. To determine the frequency of the various ultrasound findings in hand joints in patients with psoriatic arthritis and correlate grayscale and Power Doppler ultrasonography findings with Disease Activity Score 28. Methods.
Priyanka Naranje, Mahesh Prakash, Aman Sharma, Sunil Dogra, Niranjan Khandelwal   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Análise da correlação dos escores de atividade de doença na artrite reumatóide. [PDF]

, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Mello, Filipe Martins de
core  

Clinical disease activity index versus disease activity score (28 joints) for assessment of disease activity in obese patients of rheumatoid arthritis

International Journal of Advances in Medicine
Background: Measurement of disease activity by Disease Activity Score 28 joints -Erythrocyte Sedimentation Rate (DAS28-ESR), Disease Activity Score (28 joints)-C-Reactive Protein (DAS28-CRP), and Clinical Disease Activity Index (CDAI) has become an integral part of management of Rheumatoid Arthritis (RA), by ‘Treatment to Target’ approach.
Sarthak Saxena, B. K. Kundu
openaire   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source