Results 61 to 70 of about 7,943,117 (301)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Efficacious, effective, and embedded interventions: Implementation research in infectious disease control [PDF]

, 2008
Background: Research in infectious disease control is heavily skewed towards high end technology; development of new drugs, vaccines and clinical interventions.
A Garba, A Meyer, A Werner, AM Chinbuah, BR Flay, BR Flay, C Lengeler, Centre for Public Health Research, D Fixsen, D Sanders, Daniel D Reidpath, EA McCarthy, FN Binka, FN Binka, Franco Pagnoni, H Guyatt, H Pearson, H Saetren, Hashim Ghalib, J Okrah, JA DiMasi, JHF Remme, JRMA Schellenberg, K Guldbrandsson, LA Bero, M Chopra, M Eccles, M Moran, MR Bhatia, O Bhattacharyya, Pascale Allotey, PDH Molyneux, PL Alonso, R Grol, RE Glasgow, Roll Back Malaria, World Health Organization, UNICEF, TL Gary, William C Skelly, Z Obermeyer   +38 more
core   +4 more sources

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2017

EFSA Journal, 2019
The data on antimicrobial resistance in zoonotic and indicator bacteria in 2017, submitted by 28 EU Member States (MSs), were jointly analysed by EFSA and ECDC.
European Food Safety Authority, European Centre for Disease Prevention and Control   +1 more
doaj   +1 more source

UK Foot and Mouth disease: a systemic risk assessment of existing controls [PDF]

, 2016
This article details a systemic analysis of the controls in place and possible interventions available to further reduce the risk of a foot and mouth disease (FMD) outbreak in the United Kingdom.
Longhurst, Philip J., Pollard, Simon J. T., Prpich, George   +2 more
core   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from animals and food in the European Union in 2009

EFSA Journal, 2011
The European Food Safety Authority and the European Centre for Disease Prevention and Control have analysed the information on antimicrobial resistance among zoonotic and indicator bacteria in 2009 submitted by 25 European Union Member States.
European Food Safety Authority, European Centre for Disease Prevention and Control (ECDC)   +1 more
doaj   +1 more source

A two-stage meta-analysis identifies several new loci for Parkinson's disease.

PLoS Genetics, 2011
A previous genome-wide association (GWA) meta-analysis of 12,386 PD cases and 21,026 controls conducted by the International Parkinson's Disease Genomics Consortium (IPDGC) discovered or confirmed 11 Parkinson's disease (PD) loci.
International Parkinson's Disease Genomics Consortium (IPDGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)   +1 more
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source