Results 81 to 90 of about 4,372,477 (262)

Surveillance of West Nile virus infections in humans and animals in Europe, monthly report

EFSA Journal
Epidemiological summary In 2025, and as of 2 July 2025, no countries in Europe reported any locally acquired1 human cases of WNV infection with known place of infection. In the previous five years, the first locally acquired cases of the WNV transmission
European Centre for Disease Prevention and Control (ECDC), European Food Safety Authority (EFSA)   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2021–2022

EFSA Journal
This report by the European Food Safety Authority and the European Centre for Disease prevention and Control, provides an overview of the main findings of the 2021–2022 harmonised Antimicrobial Resistance (AMR) monitoring in Salmonella spp ...
European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC)   +1 more
doaj   +1 more source

Clinical pathway for diagnosis and treatment of new diagnosed multiple myeloma in Guangxi

Guangxi Yike Daxue xuebao
Multiple myeloma, an incurable clonal plasma cell dysplasia, is the second most common hematological malignancy. Standardized diagnosis and treatment are crucial for prolonging the survival of myeloma patients and improving the quality of their lives ...
The Control Center of Medical Quality of Guangxi Hematology, Guangxi Plasma Cell Disease Collaboration   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Surveillance of West Nile virus infections in humans and animals in Europe, monthly report – data submitted up to 24 June 2026

EFSA Journal
Epidemiological summary As of 24 June, two countries in Europe reported three locally acquired1 human cases of WNV infection: Italy reported two cases and North Macedonia one case. Dates of onset ranged from 12 to 27 May 2026.
European Centre for Disease Prevention and Control (ECDC), European Food Safety Authority (EFSA)   +1 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The European Union One Health 2024 Zoonoses Report

EFSA Journal
This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2024 in 27 Member States (MSs), the United Kingdom ...
European Food Safety Authority (EFSA) | European Centre for Disease Prevention and Control (ECDC)
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source