Results 81 to 90 of about 7,932,688 (301)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Genital human papillomavirus (HPV) [PDF]
Title from title screen (viewed on Oct. 31, 2011); date from document properties."HPV Common Infection, Common Reality.
Centers for Disease Control and Prevention
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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Conducting urban rodent surveys [PDF]
"This manual is for classroom use and for field training of program managers, environmental health practitioners, inspectors, outreach workers, and others who work in community-based rodent integrated pest management programs.
Centers for Disease Control and Prevention (U.S.)
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Development of disease control strategies for organically grown field vegetables (DOVE) (OF0168) [PDF]
This is the final report of Defra project OF0168 (DOVE). The attached main report starts with a more detailed and comprehensive Executive Summary, from which this text has been extracted.
Gladders, Dr Peter
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We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Parent teen driving agreement [PDF]
American Academy of Pediatrics, Centers for Disease Control and Prevention.10/6/2010 - date from document properties.Side panel: "Handing your teen the car keys--are you confident or concerned?""Parents are the key.
Centers for Disease Control and Prevention (U.S.) (issuing body.)
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