Results 1 to 10 of about 9,539,267 (257)

Comprehensive evaluation of an one pot quadruplex RT-qPCR assay for the simultaneously subtyping influenza A virus into H1, H3, N1 and N2

Journal of Clinical Virology Plus, 2022
In the current study, an one pot quadruplex RT-qPCR assay was established and comprehensively evaluated. The assay's limit of detection could reach as low as 101 copies/reaction, with good repeatability profile and no cross-reaction with other ...
Hai-Bo Wang, Ji-Can Lin, Hui-Na Huang, Jun-Ting Xu, Cheng-Ning Tu   +4 more
doaj   +1 more source

Changes in Influenza Activities Impacted by NPI Based on 4-Year Surveillance in China: Epidemic Patterns and Trends

Journal of Epidemiology and Global Health, 2023
Background Since the Non-pharmaceutical Intervention (NPI) by COVID-19 emerged, influenza activity has been somewhat altered. Objectives The aim of this study was to explore changes in influenza activities in the context of COVID-19 based on the sentinel
Jing Tan, Lijun Liang, Ping Huang, Abrar A. Ibrahim, Zhongzhou Huang, Wei Zhao, Lirong Zou   +6 more
doaj   +1 more source

Population-based bloodstream infection surveillance in rural Thailand, 2007–2014

BMC Public Health, 2019
Background Bloodstream infection (BSI) surveillance is essential to characterize the public health threat of bacteremia. We summarize BSI epidemiology in rural Thailand over an eight year period.
Julia Rhodes, Possawat Jorakate, Sirirat Makprasert, Ornuma Sangwichian, Anek Kaewpan, Thantapat Akarachotpong, Prasong Srisaengchai, Somsak Thamthitiwat, Supphachoke Khemla, Somkid Yuenprakhon, Wantana Paveenkittiporn, Anusak Kerdsin, Toni Whistler, Henry C. Baggett, Christopher J. Gregory   +14 more
doaj   +1 more source

Detecting the Neuraminidase R294K Mutation in Avian Influenza A (H7N9) Virus Using Reverse Transcription Droplet Digital PCR Method

Viruses, 2023
The R294K mutation in neuraminidase (NA) causes resistance to oseltamivir in the avian influenza virus H7N9. Reverse transcription droplet digital polymerase chain reaction (RT-dd PCR) is a novel technique for detecting single-nucleotide polymorphisms ...
Xiuyu Lou, Hao Yan, Lingxuan Su, Yi Sun, Xinyin Wang, Liming Gong, Yin Chen, Zhen Li, Zhongbiao Fang, Haiyan Mao, Keda Chen, Yanjun Zhang   +11 more
doaj   +1 more source

An educational intervention to promote appropriate antibiotic use for acute respiratory infections in a district in Egypt- pilot study

BMC Public Health, 2019
Background Antibiotic overuse is the most important modifiable factor contributing to antibiotic resistance. We conducted an educational campaign in Minya, Egypt targeting prescribers and the public through communications focused on appropriate ...
Amr Kandeel, Danielle L. Palms, Salma Afifi, Yasser Kandeel, Ahmed Etman, Lauri A. Hicks, Maha Talaat   +6 more
doaj   +1 more source

Development, roll-out and implementation of an antimicrobial resistance training curriculum harmonizes delivery of in-service training to healthcare workers in Kenya

Frontiers in Microbiology, 2023
BackgroundAntimicrobial resistance (AMR) is an increasingly severe threat to global public health that requires action across different sectors. Selection of appropriate antimicrobials is an urgent challenge due to the emergence of drug resistance.
Josiah Njeru, Joshua Odero, Sheilla Chebore, Mungai Ndung’u, Emmanuel Tanui, Emmanuel Tanui, Evelyn Wesangula, Evelyn Wesangula, Romona Ndanyi, Romona Ndanyi, Susan Githii, Susan Githii, Revathi Gunturu, Willy Mwangi, David Mutonga, Anicet Dahourou, Andrew Thaiyah   +16 more
doaj   +1 more source

Entropy of mitochondrial DNA circulating in blood is associated with hepatocellular carcinoma

BMC Medical Genomics, 2019
Background Ultra-Deep Sequencing (UDS) enabled identification of specific changes in human genome occurring in malignant tumors, with current approaches calling for the detection of specific mutations associated with certain cancers.
David S. Campo, Vishal Nayak, Ganesh Srinivasamoorthy, Yury Khudyakov   +3 more
doaj   +1 more source

Development and Evaluation of an iiPCR Assay for Salmonella and Shigella Detection on a Field-Deployable PCR System

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Background. Salmonella and Shigella are often associated with fecal-oral transmission and cause large-scale outbreaks in centralized catering units and, therefore, should be frequently and strictly monitored, especially among food handlers.
Tian Du, Ji-hong Lin, Jun-hua Zhao, Hai-bo Wang, Qiu-hua Mo   +4 more
doaj   +1 more source

Molecular Mechanisms Between Canine Parvovirus 2 and Host Interactions: From Viruses to Innate Immune Signaling Pathways

Viruses
Canine parvovirus 2 (CPV-2) is a major pathogen causing acute haemorrhagic enteritis and myocarditis in dogs. Since the discovery in the late 1970s, the original CPV-2 strain has evolved through VP2 mutations into new subtypes CPV-2a, 2b, and 2c.
Guanyu Zhao, Xinying Yang, Yuehua Li, Muzi Li, Shiping Song, Jinghan Wang, Cong Liu, Zequn Dong, Zhenhua Gong, Junhui Liu   +9 more
doaj   +1 more source

Multi-drug resistance and reduced susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates from the Middle East and Central Asia

New Microbes and New Infections, 2014
Typhoid fever is common in developing countries, with an estimated 120 million infections and 700 000 annual deaths, worldwide. Fluoroquinolones have been the treatment of choice for infection with multidrug-resistant (MDR) Salmonella enterica serovar ...
B.A. Rahman, M.O. Wasfy, M.A. Maksoud, N. Hanna, E. Dueger, B. House   +5 more
doaj   +1 more source