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Omicron or no longer omicron: That is the question

open access: yesGlobal Translational Medicine
Omicron or no longer omicron: That is the ...
Lippi, Giuseppe
openaire   +3 more sources

Immune histories and natural infection protection during the omicron era [PDF]

open access: yesCommunications Medicine
Background Past immunological events can either enhance or compromise an individual’s future immune protection. This study investigated how different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) natural infection histories before an ...
Hiam Chemaitelly   +22 more
doaj   +2 more sources

Omicron

open access: yesAPIK Journal of Internal Medicine, 2022
Emerging infectious diseases are now a concern worldwide and can evolve into a global health-care crisis or pandemic. Identification of the Omicron variant (B.1.1.529) of severe acute respiratory syndrome-2 (SARS-CoV-2) which is considered a variant of concern has added fuel to the eternal flame of the global COVID-19 pandemic.
Vasantha Kamath, Deepthi Reddy
  +11 more sources

Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody [PDF]

open access: yesScience, 2022
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has become the dominant infective strain. We report the structures of the Omicron spike trimer on its own and in complex with angiotensin-converting enzyme 2 (ACE2) or an anti-Omicron antibody.
Wanchao Yin   +25 more
openaire   +2 more sources

Omicron entry route [PDF]

open access: yesNature Reviews Immunology, 2022
Three recent preprints investigate the entry route of SARS-CoV-2 Omicron variant into host cells and its cellular and host tropism.
Luisanna Pia, Sarah Rowland-Jones
openaire   +2 more sources

MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin

open access: yesMolecular Medicine, 2022
Background The use of doxorubicin is associated with an increased risk of acute and long-term cardiomyopathy. Despite the constantly growing number of cancer survivors, little is known about the transcriptional mechanisms which progress in the time ...
Justyna Totoń-Żurańska   +12 more
doaj   +1 more source

Variants influencing age at diagnosis of HNF1A-MODY

open access: yesMolecular Medicine, 2022
Background HNF1A-MODY is a monogenic form of diabetes caused by variants in the HNF1A gene. Different HNF1A variants are associated with differences in age of disease onset, but other factors are postulated to influence this trait.
Agnieszka H. Ludwig-Słomczyńska   +15 more
doaj   +1 more source

Low Expression of miR-375 and miR-190b Differentiates Grade 3 Patients with Endometrial Cancer

open access: yesBiomolecules, 2021
Endometrial cancer (EC) is treated according to the stage and prognostic risk factors. Most EC patients are in the early stages and they are treated surgically.
Miłosz Pietrus   +5 more
doaj   +1 more source

The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes

open access: yesMolecular Medicine, 2021
Background Clinical data suggest that BMI and gestational weight gain (GWG) are strongly interconnected phenotypes; however, the genetic basis of the latter is rather unclear. Here we aim to find genes and genetic variants which influence BMI and/or GWG.
Agnieszka H. Ludwig-Słomczyńska   +10 more
doaj   +1 more source

Mitochondrial GWAS and association of nuclear – mitochondrial epistasis with BMI in T1DM patients

open access: yesBMC Medical Genomics, 2020
Background BMI is a strong indicator of complications from type I diabetes, especially under intensive treatment. Methods We have genotyped 435 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI.
Agnieszka H. Ludwig-Słomczyńska   +11 more
doaj   +1 more source

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