Results 221 to 230 of about 7,687,257 (287)

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Severe microvascular disease incidence over a 34-year period among Chinese with newly diagnosed diabetes and impaired glucose tolerance: the Da Qing diabetes outcome study 1986-2020. [PDF]

Diabetol Metab Syndr
An Q, Wang J, Huang Z, Feng X, Qian X, Zhou S, He S, Li H, Li G, Chen Y.   +9 more
europepmc   +1 more source

“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

TYG-BMI demonstrates modestly higher predictive value compared to TYG and TYG/HDL for cardiovascular disease incidence in individuals over 45: a longitudinal cohort study. [PDF]

Diabetol Metab Syndr
Chen X, Guo L, Yu Z.
europepmc   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

Advanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà, Giulia Cazzador, Roberta Fabbri, Matteo Calosi, Alessandro Silvestri, Andrea Candini, Fabiola Liscio, Franco Corticelli, Aikaterini Konstantoulaki, Andrea D'Iorio, Marco Caprini, Vincenzo Palermo, Monica Bertoldo, Valentina Benfenati, Chiara Zanardi, Emanuele Treossi   +15 more
wiley   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

TRENDS IN THE ULCERATIVE COLITIS TO CROHN'S DISEASE INCIDENCE RATIO ARE DISTINCT BETWEEN EPIDEMIOLOGIC STAGES OF INFLAMMATORY BOWEL DISEASE. [PDF]

Am J Gastroenterol
Windsor JW, Coward S, Hracs L, Mak JWY, Banerjee R, Kotze PG, Gearry R, Ng SC, Kaplan GG, Global IBD Visualization of Epidemiology Studies in the 21s,t Century (GIVES-21) Research Group.   +9 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

The combination of visceral adiposity and triglyceride-glucose indices as predictors of cardiovascular disease incidence in middle-aged and older adults. [PDF]

Eur J Med Res
Yin Y, Zhang J, Liu X, Wang L, Li X, Li Y, Li Q, Hu Z, Liang Z, Xiong R, Ning S, Wang Y.   +11 more
europepmc   +1 more source

A Single‐Solvent Acetone Strategy for Surface Enhancement and Robust Bonding in PMMA Microfluidic Devices

Advanced Materials Interfaces, EarlyView.
A single‐solvent acetone strategy simultaneously restores laser‐ablated PMMA surfaces and enables high‐strength bonding for microfluidic device fabrication. The process produces smooth, optically clear channels, achieves bonding strengths up to 27.3 MPa, and forms leak‐free devices within 25 min, providing a rapid and accessible route to robust PMMA ...
Sadık Koç, H. Cumhur Tekin
wiley   +1 more source