Results 51 to 60 of about 4,815,701 (299)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Management of Alternaria blight disease of mustard through biofungicides [PDF]

open access: yesBIO Web of Conferences
Alternaria blight, caused by Alternaria brassicae, is a major disease affecting mustard crops, leading to significant yield losses. Traditional chemical fungicides have been extensively used to manage this disease, but concerns over environmental ...
Devi Takhellambam Diparani   +3 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Foliar Fungal Disease Round-up for 2022

open access: yesEDIS, 2022
The 2021 foliar fungal season was an easier than average year. The La Niña weather pattern predicted last fall came to pass, and the spring was relatively dry from January to the end of May with some rain in February and April.
Megan M. Dewdney
doaj  

Experiences of epileptic adults with searching for and maintaining a job in the Czech republic: qualitative study

open access: yesSocial Welfare: Interdisciplinary Approach, 2018
Epilepsy is the most frequent seizure disorder affecting both social and occupational life of the patients. On the open labour market, these individuals might encounter a number of obstacles, lack of understanding, and limitations.
Jan Chrastina, Marie Vysloužilová
doaj   +1 more source

Type 1 diabetes [PDF]

open access: yes, 2018
Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past 25 years, resulting in a broad understanding about many aspects of the ...
DiMeglio, Linda A.   +2 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

A Global Survey on Diseases and Pests in Oilseed Rape—Current Challenges and Innovative Strategies of Control

open access: yesFrontiers in Agronomy, 2020
The introduction of high-yielding and hybrid cultivars and the opening of new markets in the food and feed sector have steadily increased rapeseed production since the 1980s in the main production regions, Canada, Europe, China, India, and Australia ...
Xiaorong Zheng   +3 more
doaj   +1 more source

Disc disease: A summary and review [PDF]

open access: yes, 1993
A review of the etiology, clinical, radiological and laboratory presentation, differential diagnosis and management goals of disc disease is presented.
Walker, B.F.
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

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