Results 121 to 130 of about 1,145,702 (301)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2020 People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms.
Arabnia, Hamid Reza +3 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Understanding mistreatment during institutional delivery in Northeast Nigeria: a mixed-method study
Reproductive Health, 2019 Background Improving quality of care including the clinical aspects and the experience of care has been advocated for improved coverage and better childbirth outcomes.
Nasir Umar +4 more
doaj +1 more source
Annotated bibliography of central North Island volcanic ash stratigraphy [PDF]
, 1967 Prior to 1929 many observations had been published giving brief accounts of the volcanic ash deposits in various parts of the North Island but no detailed investigations were undertaken.
Pullar, W.A., Tonkin, Philip J.
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Enhancing GeoHealth: A step-by-step procedure for spatiotemporal disease mapping
Geospatial HealthCartography, or geographical visualization of disease is an essential aspect of the field of GeoHealth, yet there is limited guidance on the visualization of spatiotemporal disease maps.
Bart Roelofs, Gerd Weitkamp
doaj +1 more source
Spatial Difference Boundary Detection for Multiple Outcomes Using Bayesian Disease Mapping. [PDF]
Biostatistics, 2023 Gao L, Banerjee S, Ritz B.
europepmc +1 more source